CAJ | 학술논문

目的探讨川崎病(KD)所引起的冠状动脉扩张(CAD)以及冠状动脉瘤(CAA)的超声心动图特点.方法用彩色多普勒超声心动图检测KD患儿冠状动脉开口和内径,并动态观察静脉免疫球蛋白治疗前后冠状动脉内径的变化情况.结果本组46例KD患儿,41例患儿行超声心动图检查,合并CAD 12例,左冠状动脉(LCA)较右冠状动脉(RCA)更易受累及(P<0.05);CAA 4例,均为双侧冠状动脉病变,最大内径10 mm.治疗后6～18 d复查超声心动图,CAD组LCA较治疗前明显回缩(P<0.05),RCA内径无变化(P>0.05);CAA组LCA和RCA内径均无明显变化(P>0.05).对10例冠状动脉病变患儿进行随访,其中8例CAD冠状动脉内径均恢复正常,1例CAA冠状动脉病变加重,1例CAA完全恢复正常.结论 (1)在KD所引起的CAD中,LCA比RCA更易受累及,静脉免疫球蛋白治疗后短期内LCA明显回缩.(2)超声心动图是动态观察KD并发CAD和CAA的无创手段.
목적 탐토천기병(KD)소인기적관상동맥확장(CAD)이급관상동맥류(CAA)적초성심동도특점.방법 용채색다보륵초성심동도검측KD환인관상동맥개구화내경,병동태관찰정맥면역구단백치료전후관상동맥내경적변화정황.결과 본조46례KD환인,41례환인행초성심동도검사,합병CAD 12례,좌관상동맥(LCA)교우관상동맥(RCA)경역수루급(P<0.05);CAA 4례,균위쌍측관상동맥병변,최대내경10 mm.치료후6～18 d복사초성심동도,CAD조LCA교치료전명현회축(P<0.05),RCA내경무변화(P>0.05);CAA조LCA화RCA내경균무명현변화(P>0.05).대10례관상동맥병변환인진행수방,기중8례CAD관상동맥내경균회복정상,1례CAA관상동맥병변가중,1례CAA완전회복정상.결론 (1)재KD소인기적CAD중,LCA비RCA경역수루급,정맥면역구단백치료후단기내LCA명현회축.(2)초성심동도시동태관찰KD병발CAD화CAA적무창수단.
Objective To evaluate the echocardiographic features of coronary artery dilation (CAD) and coronary artery aneurysms (CAA) in Kawasaki disease dynamically.Methods Echocardiography was performed in KD cases for measurement of the diameter of the coronary artery.Results Twelve CAD and four CAA were identified in forty-one patients.In CAD group,left coronary artery (LCA) is more susceptive to dilation than right coronary artery (RCA)(P<0.05).Both LCA and RCA were involved in CAA group,the maximum diameter of coronary artery is 10mm.Six to eighteen days after treatment,LCA were regressed significantly in CAD group(P<0.05),but the diameter of RCA in CAD group and coronary artery in CAA patients have no change(P>0.05).Ten coronary artery lesion patients were followed up,8 CAD cases regressed completely,1 CAA extended,the other CAA regressed completely.Conclusions In CAD group,LCA is more susceptive to dilation than RCA,but it regressed significantly in a short time after treatment.Echocardiography is a non-traumatic method to detect the coronary artery lesions in KD patients dynamically.