CAJ | 학술논문

目的探索初始血压水平对青少年远期血压变化及高血压发生的影响.方法 1987年在陕西汉中农村4623名6～15岁在校学生进行血压等相关因素调查的基础上,根据初始3次血压测量,收缩压持续稳定在该年龄、性别血压百分位数75以上者为血压偏高组,3次血压测量收缩压持续稳定在该年龄、性别血压百分位数50以下者为血压正常对照组.共有292名儿童进入队列(其中血压偏高组152名,血压正常对照组140名).2005年对该队列组样本进行随访.结果总随访率70.2%,其中血压偏高组随访率70.4%,对照组随访率70.0%;基线血压偏高组,18年后随访不仅收缩压、舒张压仍显著高于基线血压对照组,而且前者发生高血压(≥140/90 mm Hg,1 mm Hg=0.133 kPa)的概率是后者的6.88倍(28.0%对4.1%,P＜0.01).结论初始血压百分位偏高儿童,远期高血压发生率显著增加,是青年高血压发病重要易患因素.
목적 탐색초시혈압수평대청소년원기혈압변화급고혈압발생적영향.방법 1987년재협서한중농촌4623명6～15세재교학생진행혈압등상관인소조사적기출상,근거초시3차혈압측량,수축압지속은정재해년령、성별혈압백분위수75이상자위혈압편고조,3차혈압측량수축압지속은정재해년령、성별혈압백분위수50이하자위혈압정상대조조.공유292명인동진입대렬(기중혈압편고조152명,혈압정상대조조140명).2005년대해대렬조양본진행수방.결과 총수방솔70.2%,기중혈압편고조수방솔70.4%,대조조수방솔70.0%;기선혈압편고조,18년후수방불부수축압、서장압잉현저고우기선혈압대조조,이차전자발생고혈압(≥140/90 mm Hg,1 mm Hg=0.133 kPa)적개솔시후자적6.88배(28.0%대4.1%,P＜0.01).결론 초시혈압백분위편고인동,원기고혈압발생솔현저증가,시청년고혈압발병중요역환인소.
Objective Essential hypertension may begin at childhood.The aim of this study is to identify the risk factors of hypertension and detect the evolvement tracking of blood pressure in childhood.Methods In this study,we followed up blood pressure changes in 4623 school children(6-15 years-old) from 1987 to 2005 in Hanzhong rural area.A total of 152 children were grouped to higher blood pressure group[systolic blood pressure(PSBP)≥75th(P75)]and 140 children grouped to normal blood pressure group[PSBP＜50th(P50)]and their blood pressure were re-measure 18-years later. Results The total follow-up rate was 70.2%.Follow-up blood pressure was significantly higher in higher blood pressure group at baseline than that in normal blood pressure group at baseline(P＜0.05).The hypertension rate at follow up was significantly higher in higher blood pressure group at baseline than that in normal blood pressure group at baseline(28.0% vs.4.1%,P＜0.01).The risk for hypertension was 6.88 greater in higher blood pressure group at baseline than that in normal blood pressure group at baseline.Conclusions Higher blood pressure at childhood is a risk of developing hypertension at adulthood.