中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2010年
35期
2501-2503
,共3页
龚昌帆%白连启%段勇%许绍发
龔昌帆%白連啟%段勇%許紹髮
공창범%백련계%단용%허소발
结核,肺%全肺切除术%手术适应证%耐多药肺结核
結覈,肺%全肺切除術%手術適應證%耐多藥肺結覈
결핵,폐%전폐절제술%수술괄응증%내다약폐결핵
Pulmonary tuberculosis%Pneumonectomy%Surgical indication%MDR-TB
目的 探讨全肺切除治疗肺结核病的临床效果和手术适应证.方法 总结北京胸科医院胸外科1992年1月至2008年12月全肺切除的174例肺结核病患者的临床疗效.全组包括结核性毁损肺106例、慢性纤维空洞性肺结核27例、肺结核性空洞合并曲菌球5例、结核性支气管狭窄16例、支气管胸膜瘘5例、肺结核合并脓胸4例、大咯血11例.结果 全肺切除术146例、胸膜全肺切除21例、余肺切除3例、全肺切除+胸廓成形术1例、全肺切除+气管成形3例.全组临床治愈率93.0%,手术并发症率为11.5%,手术病死率为2.3%.半年内与手术有关的死亡3例.结论 虽然临床上肺结核病的主要治疗方法是抗结核药物治疗,仍有部分患者需要外科手术治疗.全肺切除术可提高重症和耐多药肺结核的临床治愈率.
目的 探討全肺切除治療肺結覈病的臨床效果和手術適應證.方法 總結北京胸科醫院胸外科1992年1月至2008年12月全肺切除的174例肺結覈病患者的臨床療效.全組包括結覈性燬損肺106例、慢性纖維空洞性肺結覈27例、肺結覈性空洞閤併麯菌毬5例、結覈性支氣管狹窄16例、支氣管胸膜瘺5例、肺結覈閤併膿胸4例、大咯血11例.結果 全肺切除術146例、胸膜全肺切除21例、餘肺切除3例、全肺切除+胸廓成形術1例、全肺切除+氣管成形3例.全組臨床治愈率93.0%,手術併髮癥率為11.5%,手術病死率為2.3%.半年內與手術有關的死亡3例.結論 雖然臨床上肺結覈病的主要治療方法是抗結覈藥物治療,仍有部分患者需要外科手術治療.全肺切除術可提高重癥和耐多藥肺結覈的臨床治愈率.
목적 탐토전폐절제치료폐결핵병적림상효과화수술괄응증.방법 총결북경흉과의원흉외과1992년1월지2008년12월전폐절제적174례폐결핵병환자적림상료효.전조포괄결핵성훼손폐106례、만성섬유공동성폐결핵27례、폐결핵성공동합병곡균구5례、결핵성지기관협착16례、지기관흉막루5례、폐결핵합병농흉4례、대각혈11례.결과 전폐절제술146례、흉막전폐절제21례、여폐절제3례、전폐절제+흉곽성형술1례、전폐절제+기관성형3례.전조림상치유솔93.0%,수술병발증솔위11.5%,수술병사솔위2.3%.반년내여수술유관적사망3례.결론 수연림상상폐결핵병적주요치료방법시항결핵약물치료,잉유부분환자수요외과수술치료.전폐절제술가제고중증화내다약폐결핵적림상치유솔.
Objective To evaluate the efficacy and indication of pneumonectomy in patients with pulmonary tuberculosis. Methods From January 1992 to the end of 2008, 174 patients with pulmonary tuberculosis underwent pneumonectomy. According to the classification of pulmonary tuberculosis, there were tuberculous destroyed lungs ( n = 106 ), chronic fibro-cavernous pulmonary tuberculosis ( n = 27 ), cavernous pulmonary tuberculosis with aspergilloma ( n = 5 ), tuberculous tracheobronchial stenosis (n =16),pulmonary tuberculosis with encapsulated empyema (n = 5), tuberculous empyema with broncho pleural fistula ( n = 4) and massive hemoptysis (n = 11). Results The surgical approaches were pneumonectomy (n = 146 ), pleuropneumonectomy ( n = 21 ), chlorine pneumonectomy ( n = 3 ), pneumonectomy with thoracoplasty (n = 1 ) and pneumonectomy with tracheoplasty ( n = 3). The overall clinical cure rate was 93.0%, the rate of complications 11.5% and the operative mortality 2. 3%. There were 3 dead cases resulting from operations in six months. Conclusion Tuberculosis chemotherapy is an important modality for pulmonary tuberculosis, but surgical therapy remains essential for some patients. Pneumonectomy may increase the cure rates of severe pulmonary and multiple drug resistant tuberculosis.