CAJ | 학술논문

目的: 比较轻型胰腺炎病人早期摄食与禁食两种治疗措施的安全性和对病情转归的影响.方法: 将72例急性轻型胰腺炎病人随机分为A(早期摄食)组与B(禁食治疗)组.对入选病人治疗过程中,淀粉酶水平、炎症反应和平均住院时间进行评价.结果: A组病人淀粉酶水平、C反应蛋白、WBC计数、腹痛或消化道症状与B组无显著性差异,但平均住院时间明显缩短(P<0.05).结论: 在急性轻型胰腺炎病人的治疗过程中,采取早期摄食不仅不会加重病情,而且还会促进病人康复.
목적: 비교경형이선염병인조기섭식여금식량충치료조시적안전성화대병정전귀적영향.방법: 장72례급성경형이선염병인수궤분위A(조기섭식)조여B(금식치료)조.대입선병인치료과정중,정분매수평、염증반응화평균주원시간진행평개.결과: A조병인정분매수평、C반응단백、WBC계수、복통혹소화도증상여B조무현저성차이,단평균주원시간명현축단(P<0.05).결론: 재급성경형이선염병인적치료과정중,채취조기섭식불부불회가중병정,이차환회촉진병인강복.
Objective: In acute pancreatitis, traditional treatment insists fasting on purpose to avoid activation of proteolytic enzymes and pancreatic enzyme secretion. The aim of our study was to evaluate the efficacy and feasibility of early oral feeding as compared to traditional fasting in patients with mild acute pancreatitis.Methods: Seventy-two patients were randomized to the two treatment groups, fasting or early oral feeding. The inclusion criteria were pancreas amylase≥3times above normal, onset of abdominal pain within 48h, acute physiological and chronic health evaluation-II score<8 and C-reactive protein(CRP)<150 mg/L. Measures were amylase, systemic inflammatory response, length of hospital stay. Results: The groups were comparable with respect to age, sex, etiology, APACHE II, time from onset of pain and amylase at admission. No significant differences were seen between the groups concerning levels of amylase, CRP, leukocytes, abdominal pain or number of gastrointestinal symptoms. The length of hospital stay time was significantly shorter in the oral feeding group (13 vs. 17 days; P<0.05).Conclusion: Early oral feeding would not exacerbate disease process. The differences between treatment groups for amylase or systemic inflammatory response were not obvious. In mild acute pancreatitis, early oral feeding was feasible and safe and may accelerate recovery.