CAJ | 학술논문

分子生物学研究方法的快速发展给综合性遗传研究实验室的实验和数据管理工作提出了严峻的挑战.针对基因分型实验室的特点和需求,对基于SNP实验流程的信息管理系统进行了扩展和升级,在原有LIMS系统所包括的3个SNP分型实验管理模块的基础上,扩展到包括多类基因分型实验的8个实验管理模块,并增加了数据处理、报表展示等模块,完善了数据查询、导出功能,为遗传基因分型实验数据管理与分析提供更全面的支持.本文简要介绍系统的框架结构、设计实现和主要功能.
분자생물학연구방법적쾌속발전급종합성유전연구실험실적실험화수거관리공작제출료엄준적도전.침대기인분형실험실적특점화수구,대기우SNP실험류정적신식관리계통진행료확전화승급,재원유LIMS계통소포괄적3개SNP분형실험관리모괴적기출상,확전도포괄다류기인분형실험적8개실험관리모괴,병증가료수거처리、보표전시등모괴,완선료수거사순、도출공능,위유전기인분형실험수거관리여분석제공경전면적지지.본문간요개소계통적광가결구、설계실현화주요공능.
The rapid development of molecular biology research methods pose a severe chaLlenge for a comprehensive study of genetic laboratory experiments and data management. Previously reported SNP LIMS was upgraded to a data processing platform based on re-quirements raised by the genotyping laboratory of Chinese National Human Genetics Center at Shanghai (CHGC). Laboratory informa-tion management system was expanded to manage eight experiment platforms, up from the previous three platforms. The data process-ing, form presentation, queries and data export modules were greatly enhanced. This system can now provide much wider support for data management and data analysis work of a modern genotyping laboratory. In this paper the authors discussed the overall design and architecture, as well as the main functional modules of this system.