CAJ | 학술논문

目的探讨甲状腺乳头状癌超声造影的增强模式,评价超声造影对甲状腺乳头状癌的诊断价值.方法 2007年1月至2008年10月浙江舟山医院超声科,应用微泡造影剂SonoVue及对比脉冲序列(CPS)造影成像技术对122例甲状腺占位性病变患者行检查,回顾性分析其中31例35灶甲状腺乳头状癌的超声造影增强表现.结果 35灶甲状腺乳头状癌造影后增强表现可分为3种模式:模式Ⅰ,病灶呈环状不规则缓慢向心性填充(23灶),但中心部分未见造影剂充填;模式Ⅱ,整体均匀性增强(5灶);模式Ⅲ,整体不均匀性增强(7灶).甲状腺良、恶性病灶灌注时间曲线相比较,甲状腺乳头状癌与结节性甲状腺肿相比较造影剂到达时间(AT)、达峰时间(TTP)和开始消退时间(WT)三项指标差异均有统计学意义(均P<0.05);甲状腺乳头状癌与甲状腺腺瘤相比较仅WT一项指标差异有统计学意义(P<0.05).结论常规超声诊断困难的甲状腺癌超声造影后根据其典型增强模式,多数可作出明确的诊断.
목적 탐토갑상선유두상암초성조영적증강모식,평개초성조영대갑상선유두상암적진단개치.방법 2007년1월지2008년10월절강주산의원초성과,응용미포조영제SonoVue급대비맥충서렬(CPS)조영성상기술대122례갑상선점위성병변환자행검사,회고성분석기중31례35조갑상선유두상암적초성조영증강표현.결과 35조갑상선유두상암조영후증강표현가분위3충모식:모식Ⅰ,병조정배상불규칙완만향심성전충(23조),단중심부분미견조영제충전;모식Ⅱ,정체균균성증강(5조);모식Ⅲ,정체불균균성증강(7조).갑상선량、악성병조관주시간곡선상비교,갑상선유두상암여결절성갑상선종상비교조영제도체시간(AT)、체봉시간(TTP)화개시소퇴시간(WT)삼항지표차이균유통계학의의(균P<0.05);갑상선유두상암여갑상선선류상비교부WT일항지표차이유통계학의의(P<0.05).결론 상규초성진단곤난적갑상선암초성조영후근거기전형증강모식,다수가작출명학적진단.
Objective To investigate the enhancement pattern of thyroid carcinoma with contrast-enhanced ultrasound (CEUS) for the diagnostic value. Methods Thirty-one cases with thirty-five thyroid Occupied were retrospectively reviewed. The final diagnosis was confirmed by biopsy pathology. Contrast agent SonoVue and contrast pulse sequencing (CPS) technique were used in this study. Results Thirty-five thyroid carcinoma presented three enhancement patterns with CEUS. Type I : twenty-three lesions enhanced in a pattern of ring with centripetal fill-in,however, the central part of no contrast agent filling . Type Ⅱ : five lesions enhanced regularly and homogeneously . Type Ⅲ: seven lesions enhanced irregularly and homogeneously. Thyroid benign and malignant lesions perfusion time curve, compared to papillary thyroid carcinoma with nodular goiter in the AT, TTP and WT indicators P <0. 05 ; papillary thyroid carcinoma and thyroid adenoma, compared to WT alone an indicator of P < 0.05. Conclusions Identification of the different enhancement patterns of thyroid carcinoma could improve the diagnostic ability of CEUS.