中华内分泌外科杂志
中華內分泌外科雜誌
중화내분비외과잡지
CHINESE JOURNAL OF ENDOCRINE SURGERY
2009年
3期
167-169
,共3页
分化型甲状腺癌术后%131碘清除
分化型甲狀腺癌術後%131碘清除
분화형갑상선암술후%131전청제
Differentiated thyroid cancer (DTC)%Iodine-131 ablation
目的 观察131I首次"清甲"的疗效及分析其影响因素.方法 确诊分化型甲状腺癌(DTC)患者经手术治疗后行131I治疗,然后按手术方式、术后治疗时间、131I的剂量进行分类,观察首次"清甲"的疗效.结果 "清甲"成功率:甲状腺全切88.5%,次全切除44.4%;"清甲"时间术后1～2个月92.7%,1年以上50.0%;131I剂量2.96 GBq为47.6%,4.44 GBq为82.8%.结论 DTC治疗应以甲状腺全切及颈淋巴结清扫为首选治疗方式,术后1～2个月为131I"清甲"最佳时机,首次"清甲"131I剂量以4.44 GBq(120mci)为宜.
目的 觀察131I首次"清甲"的療效及分析其影響因素.方法 確診分化型甲狀腺癌(DTC)患者經手術治療後行131I治療,然後按手術方式、術後治療時間、131I的劑量進行分類,觀察首次"清甲"的療效.結果 "清甲"成功率:甲狀腺全切88.5%,次全切除44.4%;"清甲"時間術後1～2箇月92.7%,1年以上50.0%;131I劑量2.96 GBq為47.6%,4.44 GBq為82.8%.結論 DTC治療應以甲狀腺全切及頸淋巴結清掃為首選治療方式,術後1～2箇月為131I"清甲"最佳時機,首次"清甲"131I劑量以4.44 GBq(120mci)為宜.
목적 관찰131I수차"청갑"적료효급분석기영향인소.방법 학진분화형갑상선암(DTC)환자경수술치료후행131I치료,연후안수술방식、술후치료시간、131I적제량진행분류,관찰수차"청갑"적료효.결과 "청갑"성공솔:갑상선전절88.5%,차전절제44.4%;"청갑"시간술후1～2개월92.7%,1년이상50.0%;131I제량2.96 GBq위47.6%,4.44 GBq위82.8%.결론 DTC치료응이갑상선전절급경림파결청소위수선치료방식,술후1～2개월위131I"청갑"최가시궤,수차"청갑"131I제량이4.44 GBq(120mci)위의.
Objective To observe the effect of the first iodine-131 ablation of thyroid remnants in pa-tients with differentiated thyroid cancer (DTC) and discuss factors that may be influential in the treatment. Meth-ods All DTC patients confirmed by pathology received iodine-131 therapy after necessary preparation. Accord-ing different operation procedures, time interval between operation and iodine-131 treatment and dose of iodine - 131, the patients were divided into different groups. Therapy effects were observed in different groups. Results Ablation successful rate was 88.5% in total thyroidectomy group, compared with 44.4% in subtotal thyroidecto-my group. 92.7% ablation rate was seen in the group of I-2 months time interval between operation and iodine - 131 treatment, while in the group of over 1 year time interval, only 50% ablationrate was achieved. Ablation successful rate was 47.6% in the group of low dose of iodine-131 (2.96GBq), compared with 82.8% in the high dose group (4.44GBq). Conclusions Total thyroidectomy and cervical lymph nodes dissection should be recommended for the patients with DTC. The better interval time between operation and iodine-131 ablation thy-roid remnants is 1～2 months. The high dose of iodine-131 shows better result than low dose of iodine-131 treatment.
