CAJ | 학술논문

目的通过对512例急性肾绞痛治疗效果的回顾性分析,对常用的几种药物缓解疼痛的方法进行比较,寻找毒麻药外的有效治疗肾绞痛方法,为社区急性肾绞痛药物治疗提供对策.方法对512例中重度肾绞痛患者(口述评分法制定疼痛的严重程度),按照我院常用的3种治疗方法随机分为三组:(1)哌替啶+654-2;(2)氯诺昔康+654-2;(3)罗通定+654-2,评价给药40分钟内疼痛缓解的效果并进行组间比较分析.结果哌替啶组显效率86%,有效率90%,氯诺昔康组显效率70%,有效率92%,罗通定组显效率65%,有效率率89%,后两组的显效不及哌替啶(P＜0.05),而三组的有效率差异无显著性(P＞0.05).结论氯诺昔康、罗通定可以替代哌替啶治疗中重度肾绞痛,可在社区推广应用.
목적 통과대512례급성신교통치료효과적회고성분석,대상용적궤충약물완해동통적방법진행비교,심조독마약외적유효치료신교통방법,위사구급성신교통약물치료제공대책.방법 대512례중중도신교통환자(구술평분법제정동통적엄중정도),안조아원상용적3충치료방법수궤분위삼조:(1)고체정+654-2;(2)록낙석강+654-2;(3)라통정+654-2,평개급약40분종내동통완해적효과병진행조간비교분석.결과 고체정조현효솔86%,유효솔90%,록낙석강조현효솔70%,유효솔92%,라통정조현효솔65%,유효솔솔89%,후량조적현효불급고체정(P＜0.05),이삼조적유효솔차이무현저성(P＞0.05).결론 록낙석강、라통정가이체대고체정치료중중도신교통,가재사구추엄응용.
Object To investigate the effective therapeutic to control nephric colic without anesthetics by comparing the different drugs. Methods 512 patients with moderate or severe nephric colic (the severity of pain was scored by verbal report) were randomized into three groups, including (1) group pethidine +654-2, (2) group lornoxicam + 654-2,and (3) group rotundine +654-2. The effects on alleviation of pain were evaluated among three groups within 40 minutes after drug administration.Results The excellence rate iss 86% and effective rate is 90% in group pethidine + 654-2. The excellence rate are 70% and 65%, respectively,in group lornoxicam + 654-2 and group rotundine +654-2, which are both lower than that in group pethidine +654-2 (both P＜ 0.05), however, the effective rates were 92% and 89%, respectively, which are not significantly different from that in group pethidin + 654-2 (both P＞ 0.05). Comclusion Lornoxicam and rotundine can be widely used to replace pethidine to alleviate nephric colic.