中华神经科杂志
中華神經科雜誌
중화신경과잡지
Chinese Journal of Neurology
2011年
11期
739-741
,共3页
诊断技术,神经病学%经颅磁刺激%电刺激%参考值
診斷技術,神經病學%經顱磁刺激%電刺激%參攷值
진단기술,신경병학%경로자자격%전자격%삼고치
Diagnostic techniques,neurological%Transcranial magnetic stimulation%Electric stimulation%Reference values
目的 在健康志愿者中检验三重刺激技术(TST)的可靠性,并探讨其在中国汉族人群中的正常参考值.方法 对2010年4月至2011年2月来自北京大学第三医院神经科的100名健康志愿者进行了双侧小指展肌TST检测,结合经颅磁刺激和外周刺激,应用对冲技术,给予3个刺激,发生2次对冲.3个刺激分别为磁刺激皮质运动区、电刺激腕部、电刺激Erb点.TST检测的顺序是:经颅磁刺激→在腕部电刺激→在Erb点电刺激;TST对照的顺序:在Erb点电刺激→在腕部电刺激→在Erb点电刺激.结果以TST检测/TST对照波幅比率表示,采用配对样本t检验及单因素方差分析,同时比较不同性别、年龄、臂长以及左右侧之间的数值.结果 全部受试者的TST检测/TST对照波幅比率为85.0％±6.7％.受试者左、右侧TST数值以及不同性别、不同年龄组之间差异均无统计学意义.臂长61～70 cm的受试者(50名)和臂长71 ～ 80 cm的受试者(50名)TST数值分别为85.0％±2.6％和85.0％±8.7％,组间比较差异同样无统计学意义.结论 TST检测方法比较完善,不受年龄、侧别、性别、臂长的影响,可试用于锥体束功能的检测.
目的 在健康誌願者中檢驗三重刺激技術(TST)的可靠性,併探討其在中國漢族人群中的正常參攷值.方法 對2010年4月至2011年2月來自北京大學第三醫院神經科的100名健康誌願者進行瞭雙側小指展肌TST檢測,結閤經顱磁刺激和外週刺激,應用對遲技術,給予3箇刺激,髮生2次對遲.3箇刺激分彆為磁刺激皮質運動區、電刺激腕部、電刺激Erb點.TST檢測的順序是:經顱磁刺激→在腕部電刺激→在Erb點電刺激;TST對照的順序:在Erb點電刺激→在腕部電刺激→在Erb點電刺激.結果以TST檢測/TST對照波幅比率錶示,採用配對樣本t檢驗及單因素方差分析,同時比較不同性彆、年齡、臂長以及左右側之間的數值.結果 全部受試者的TST檢測/TST對照波幅比率為85.0％±6.7％.受試者左、右側TST數值以及不同性彆、不同年齡組之間差異均無統計學意義.臂長61～70 cm的受試者(50名)和臂長71 ～ 80 cm的受試者(50名)TST數值分彆為85.0％±2.6％和85.0％±8.7％,組間比較差異同樣無統計學意義.結論 TST檢測方法比較完善,不受年齡、側彆、性彆、臂長的影響,可試用于錐體束功能的檢測.
목적 재건강지원자중검험삼중자격기술(TST)적가고성,병탐토기재중국한족인군중적정상삼고치.방법 대2010년4월지2011년2월래자북경대학제삼의원신경과적100명건강지원자진행료쌍측소지전기TST검측,결합경로자자격화외주자격,응용대충기술,급여3개자격,발생2차대충.3개자격분별위자자격피질운동구、전자격완부、전자격Erb점.TST검측적순서시:경로자자격→재완부전자격→재Erb점전자격;TST대조적순서:재Erb점전자격→재완부전자격→재Erb점전자격.결과이TST검측/TST대조파폭비솔표시,채용배대양본t검험급단인소방차분석,동시비교불동성별、년령、비장이급좌우측지간적수치.결과 전부수시자적TST검측/TST대조파폭비솔위85.0％±6.7％.수시자좌、우측TST수치이급불동성별、불동년령조지간차이균무통계학의의.비장61～70 cm적수시자(50명)화비장71 ～ 80 cm적수시자(50명)TST수치분별위85.0％±2.6％화85.0％±8.7％,조간비교차이동양무통계학의의.결론 TST검측방법비교완선,불수년령、측별、성별、비장적영향,가시용우추체속공능적검측.
Objective To validate the technique and to establish the reference values of triple stimulation technique(TST)in healthy Chinese adults.Methods One hundred healthy subjects were recruited to undergo TST from April 2010 to February 2011 in both abductor digiti minimi.The TST combines transcranial magnetic stimulation(TMS)of the motor cortex with peripheral collision studies.Three stimuli were given,leading to two collisions.A first magnetic stimulus was applied to the scalp overlying the motor cortex.After a delay,an electric stimulus was applied over the ulnar nerve at the wrist.The delay was chosen so that the action potentials descending from the cortex collided with the antidromic action potentials evoked at the wrist,with the collision site at the wrist and above.After another delay,another electrical stimulus was applied to Erb' s point.This delay was chosen so that ascending antidromic action potentials evoked by wrist stimulation collided at or distal to Erb' s point.At the same time,TST test curves were recorded.The TST test curve was compared with a TST control curve in which the first stimulus was applied to Erb' s point and the other two stimulus sites were the same as the test curve.Control stimuli were thus applied successively to Erb' s point,the wrist,Erb' s point.TST quantifies the number of conducting central motor neurons(expressed by the TST amplitude ratio).The values were compared among genders,age groups,arm length and sides respectively.Results The TST amplitude ratio(TSTteat/TSTcontrol)was 85.0％ ± 6.7％.There were no difference among genders,age groups,arm length and sides respectively.The TST amplitude ratio were 85.0％ ± 2.6％ and 85.0％ ± 8.7％,respectively in subjects with arm length 61-70 cm and 71-80 cm.Conclusion TST could be examined precisely and the normative value could be got.
