CAJ | 학술논문

目的探讨进行抗生素皮肤过敏试验前曾经口服抗生素是否对皮试结果有影响,以及影响抗生素皮试阳性的相关因素,为护士进行规范使用抗生素的健康教育提供依据.方法对130例没有药物过敏史的患者做头孢菌素和青霉素类两种抗生素皮试,观察皮试结果与皮试前是否口服抗生素的关系.结果头孢菌素类和青霉素类两种抗生素皮试的阳性率差异无统计学意义;皮试前口服过抗生素的患者阳性率高于未服过抗生素的患者;皮试阳性率与患者的性别、年龄、皮试药物无相关性,与皮试前服用抗生素有相关性.结论在做抗生素皮试时,护理人员应对虽无药物过敏史但皮试前曾服用过抗生素的患者加强观察.
목적 탐토진행항생소피부과민시험전증경구복항생소시부대피시결과유영향,이급영향항생소피시양성적상관인소,위호사진행규범사용항생소적건강교육제공의거.방법 대130례몰유약물과민사적환자주두포균소화청매소류량충항생소피시,관찰피시결과여피시전시부구복항생소적관계.결과 두포균소류화청매소류량충항생소피시적양성솔차이무통계학의의;피시전구복과항생소적환자양성솔고우미복과항생소적환자;피시양성솔여환자적성별、년령、피시약물무상관성,여피시전복용항생소유상관성.결론 재주항생소피시시,호리인원응대수무약물과민사단피시전증복용과항생소적환자가강관찰.
Objective To explore whether there are effects of oral antibiotics before skin anaphylaxis test to antibiotics on the results of skin test, and the related factors influencing the positive skin test in antibiotics, so as to provide evidences for health education for nurses' standard use of antibiotics. Methods 130 patients who had no allergic history of medications underwent antibiotic skin test. The correlation between results of skin test and whether taking antibiotics orally before skin test was observed. Results There was no statistical meaning between the positive rates of skin tests for cephalesporin antibiotics and penicillins antibiotics; the positive rate of patients who took antibiotics orally before the skin test was higher than that of patients who took no antibiotics; the positive rate of skin test had no correlation with the age and sex of patients as well as the drugs for skin test, but there was correlation with taking antibiotics before skin test. Conclusions When conducting the skin anaphylaxis test to antibiotics, nurses should strictly observe the patients who have no allergic history of medications but take antibiotics orally before skin test.