中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2009年
7期
76-78
,共3页
老年%急性心肌梗死%溶栓治疗
老年%急性心肌梗死%溶栓治療
노년%급성심기경사%용전치료
Geratic%Acute myocardial infarction%Thrombolytic therapy
目的 比较老年急性心肌梗死(acute mrocardialinfarction,AMI)发病后不同时间窗静脉溶栓治疗效果.方法 120例老年AMI患者按发病到溶栓治疗开始时间分为<5 h(5 h)组和6～12 h组(延迟组),在AMI常规治疗的基础上予尿激酶(UK)150万u溶栓治疗.结果 5h组血管再通率、4周病死率、严重心衰发生率、半年后左室射血分数(LVEF)分别为71.67%、3.33%、6.67%、(63±8.1)%;延迟组血管再通率、4周病死率、严重心衰发生率、半年后LVEF分别为15.0%、13.33%、12.0%、(51.5±9.5)%两组比较有统计学差异(P<0.01及P<0.05),而出血并发症的发生率,两组无统计学差异(P>0.05).结论 5h组血管再通率,LVEF较高,4周病死率低.
目的 比較老年急性心肌梗死(acute mrocardialinfarction,AMI)髮病後不同時間窗靜脈溶栓治療效果.方法 120例老年AMI患者按髮病到溶栓治療開始時間分為<5 h(5 h)組和6～12 h組(延遲組),在AMI常規治療的基礎上予尿激酶(UK)150萬u溶栓治療.結果 5h組血管再通率、4週病死率、嚴重心衰髮生率、半年後左室射血分數(LVEF)分彆為71.67%、3.33%、6.67%、(63±8.1)%;延遲組血管再通率、4週病死率、嚴重心衰髮生率、半年後LVEF分彆為15.0%、13.33%、12.0%、(51.5±9.5)%兩組比較有統計學差異(P<0.01及P<0.05),而齣血併髮癥的髮生率,兩組無統計學差異(P>0.05).結論 5h組血管再通率,LVEF較高,4週病死率低.
목적 비교노년급성심기경사(acute mrocardialinfarction,AMI)발병후불동시간창정맥용전치료효과.방법 120례노년AMI환자안발병도용전치료개시시간분위<5 h(5 h)조화6～12 h조(연지조),재AMI상규치료적기출상여뇨격매(UK)150만u용전치료.결과 5h조혈관재통솔、4주병사솔、엄중심쇠발생솔、반년후좌실사혈분수(LVEF)분별위71.67%、3.33%、6.67%、(63±8.1)%;연지조혈관재통솔、4주병사솔、엄중심쇠발생솔、반년후LVEF분별위15.0%、13.33%、12.0%、(51.5±9.5)%량조비교유통계학차이(P<0.01급P<0.05),이출혈병발증적발생솔,량조무통계학차이(P>0.05).결론 5h조혈관재통솔,LVEF교고,4주병사솔저.
Objective To compare the effect of thrombolytic therapy on acute myocardial patients when it is given at different times after the onset of heart attack symptoms. Methods A total of 120 patiens with acute myocardial infarction were divided into two groups;an early group and a late group. The early group were the pa-tients who had begun to receive the therapy less than 6 hours after the onset of their symptoms, and the late group were the patiens who had begun to receive the therapy more than 6 hours after the onset of their symptoms. In ac-cordance with standard thrombolytic therapy practice, urokinase 1500000U was administered intravenously. Re-suits 5 h group vascular recanalization rate, the mortality rate after four weeks, the incidence of serious heart failure, six months after the left ventricular ejection fraction (LVEF) were 71.67%, 3.33%, 6. 67%, (63± 8.1) % ; the delayed group vascular recanalization rate, mortality rate four weeks, the incidence of serious heart failure, LVEF after six months were 15.0% , 13.33%, 12.0% , (51.5±9.5) %. There was significant differ-ence between the two groups in this respect(P<0.01 ,P<0.05) ,but it should be noted that there was no sig-nificant difference in the rate of heamorrage between the two groups (P>0.05 ). Conclusion The<5 h group showed much better results. , not only both vascular recanalization rate and the LVEF were significantly higher than in the delayed group, but also the mortality rate after four weeks was much lower too.
