CAJ | 학술논문

目的探讨实时超声剪切成像(supersonic shear imaging,SSI)的定量超声弹性图在肢体挤压伤所致局部肌肉损伤中的价值.方法健康新西兰白兔23只,使用袖带气囊加压法于兔后腿制作肌肉挤压伤动物模型.于解压后30 min、2h、6h、24 h、72 h分别进行实时超声组织弹性成像,获取肌肉组织的弹性值,分析使用组织弹性值评价肌肉损伤程度的准确性.结果 23只兔全部建模成功.左后腿挤压伤面积占体表面积的2.6％～3.0％.灰阶超声显示左后腿肌肉的挤压部分与非挤压部分分界清晰.解压后30 min、2h、6h、24 h、72 h的最大弹性值分别为(19.51±6.74)kPa、(21.47±5.54)kPa、(11.36±5.35)kPa、(15.09±3.31)kPa、(13.72±3.74)kPa,平均弹性值分别为(12.44±3.77)kPa、(13.20±3.60)kPa、(6.80±2.86)kPa、(10.04±2.95)kPa、(6.94±0.97)kPa,均显著高于非挤压区的最大弹性值和平均弹性值(P＜0.001).ROC曲线显示,使用最大弹性值和平均弹性值能够诊断肢体肌肉挤压区,且弹性值越大,诊断价值越大.结论肢体肌肉挤压伤的弹性平均值与弹性最大值可以定量测定挤压区组织弹性变化,反映组织的硬度和压力变化,在诊断肢体肌肉挤压伤中是常规超声有价值的补充.
목적 탐토실시초성전절성상(supersonic shear imaging,SSI)적정량초성탄성도재지체제압상소치국부기육손상중적개치.방법 건강신서란백토23지,사용수대기낭가압법우토후퇴제작기육제압상동물모형.우해압후30 min、2h、6h、24 h、72 h분별진행실시초성조직탄성성상,획취기육조직적탄성치,분석사용조직탄성치평개기육손상정도적준학성.결과 23지토전부건모성공.좌후퇴제압상면적점체표면적적2.6％～3.0％.회계초성현시좌후퇴기육적제압부분여비제압부분분계청석.해압후30 min、2h、6h、24 h、72 h적최대탄성치분별위(19.51±6.74)kPa、(21.47±5.54)kPa、(11.36±5.35)kPa、(15.09±3.31)kPa、(13.72±3.74)kPa,평균탄성치분별위(12.44±3.77)kPa、(13.20±3.60)kPa、(6.80±2.86)kPa、(10.04±2.95)kPa、(6.94±0.97)kPa,균현저고우비제압구적최대탄성치화평균탄성치(P＜0.001).ROC곡선현시,사용최대탄성치화평균탄성치능구진단지체기육제압구,차탄성치월대,진단개치월대.결론 지체기육제압상적탄성평균치여탄성최대치가이정량측정제압구조직탄성변화,반영조직적경도화압력변화,재진단지체기육제압상중시상규초성유개치적보충.
Objective To explore the appearance of muscle crush injury at quantitative ultrasonographic elastography by supersonic shear imaging (SSI).Methods The animal experiment was done using a special balloon cuff device to create left hind leg crush injury with a force of 18.6 kPa.Twentythree New Zealand rabbits had crush injury of extremity and survived for 72 hours.SSI quantitative elastography was performed in crushed and no-crushed regions of each rabbit hind leg.Quantitative lesion elasticity was measured in terms of the Young modulus (in kilopascals) at 30 min,2 h,6 h,24 h and 72 h after the release of the crushing pressure.A receiver operating characteristic (ROC) curve analysis was used to assess diagnostic performance.Results The area of crushed region in left hind leg accounted for 2.6％ -3.0％ of body surface area in 23 rabbits.The crushed regions exhibited maximum elasticity values of (19.51 ± 6.74)kPa,(21.47 ± 5.54) Pa,(11.36 ± 5.35)kPa,(15.09 ± 3.31)kPa and (13.72 ± 3.74) kPa,and mean elasticity values of (12.44 ± 3.77)kPa,(13.20 ± 3.60)kPa,(6.80±2.86)kPa,(10.04 ± 2.95)kPa and (6.94 ± 0.97)kPa at 30 min,2 h,6 h,24 h and 72 h after the release of the crushing pressure.Comparing with those of no-crushed regions,they were higher obviously (P＜0.001).ROC curves showed that extremity crush injury was diagnosed by using elasticity value,and the greater the elasticity value,the greater the diagnostic value.Conclusions SSI provides quantitative elasticity measurements,thus adding complementary information that potentially could help in crush injury characterization with conventional ultrasonography.