中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2011年
10期
1009-1012
,共4页
孙艳%林丽钦%康跃凡%郑备红%林典梁
孫豔%林麗欽%康躍凡%鄭備紅%林典樑
손염%림려흠%강약범%정비홍%림전량
锌%铜%受精,体外%胚胎移植%卵泡液
鋅%銅%受精,體外%胚胎移植%卵泡液
자%동%수정,체외%배태이식%란포액
Zinc%Copper%In vitro fertilization%Embryo transfer%Follicular fluid
目的 探讨微量元素锌、铜元素与体外受精-胚胎移植(IVF-ET)临床结局的关系.方法 回顾性分析43例IVF-ET治疗周期的临床资料以及绒毛膜促性腺激素(hCG)注射日血清和取卵日卵泡液内锌、铜元素含量.结果 应用Pearson相关分析显示,在43例治疗周期中卵泡液内铜浓度与获卵数、受精数和卵裂数呈正相关关系(r值分别为0.392、0.327和0.321,P值分别为0.0094、0.0325和0.0361).临床妊娠组与未妊娠组相比,卵泡液内锌、铜元素浓度差异均无统计学意义(P均＞0.05)；hCG注射日血清雌二醇差异有统计学意义[(4513.65±2538.3) ng/L与(6495.29±3402.8)ng/L,t=2.177,P=0.0353]；hCG注射日血清锌含量差异有统计学意义[(98.60±18.08) μmol/L与(87.89±10.61) μmol/L,t =2.153,P=0.0372].结论 微量元素锌、铜在IVF-ET过程中可能发挥着重要作用.
目的 探討微量元素鋅、銅元素與體外受精-胚胎移植(IVF-ET)臨床結跼的關繫.方法 迴顧性分析43例IVF-ET治療週期的臨床資料以及絨毛膜促性腺激素(hCG)註射日血清和取卵日卵泡液內鋅、銅元素含量.結果 應用Pearson相關分析顯示,在43例治療週期中卵泡液內銅濃度與穫卵數、受精數和卵裂數呈正相關關繫(r值分彆為0.392、0.327和0.321,P值分彆為0.0094、0.0325和0.0361).臨床妊娠組與未妊娠組相比,卵泡液內鋅、銅元素濃度差異均無統計學意義(P均＞0.05)；hCG註射日血清雌二醇差異有統計學意義[(4513.65±2538.3) ng/L與(6495.29±3402.8)ng/L,t=2.177,P=0.0353]；hCG註射日血清鋅含量差異有統計學意義[(98.60±18.08) μmol/L與(87.89±10.61) μmol/L,t =2.153,P=0.0372].結論 微量元素鋅、銅在IVF-ET過程中可能髮揮著重要作用.
목적 탐토미량원소자、동원소여체외수정-배태이식(IVF-ET)림상결국적관계.방법 회고성분석43례IVF-ET치료주기적림상자료이급융모막촉성선격소(hCG)주사일혈청화취란일란포액내자、동원소함량.결과 응용Pearson상관분석현시,재43례치료주기중란포액내동농도여획란수、수정수화란렬수정정상관관계(r치분별위0.392、0.327화0.321,P치분별위0.0094、0.0325화0.0361).림상임신조여미임신조상비,란포액내자、동원소농도차이균무통계학의의(P균＞0.05)；hCG주사일혈청자이순차이유통계학의의[(4513.65±2538.3) ng/L여(6495.29±3402.8)ng/L,t=2.177,P=0.0353]；hCG주사일혈청자함량차이유통계학의의[(98.60±18.08) μmol/L여(87.89±10.61) μmol/L,t =2.153,P=0.0372].결론 미량원소자、동재IVF-ET과정중가능발휘착중요작용.
Objective To investigate the relationship between the zinc and copper concentration and the clinical outcomes of in vitro fertilization and embryo transfer(ivf-et).Methods The clinical data and zinc and copper concentration of serum on the days with human Chorionic gonadotropin(hCG) injection as well as that in the follicular fluid on the the day of oocyte retrieval were retrospectively analyzed in 43 cases with IVF-ET cycles.Results Application of pearson correlation analysis showed that copper concentration in follicular fluid of the 43 cases was positively correlated with the numbers of retrieved oocytes,fertilized oocytes and cleaved embryos( r were 0.392,0.327 and 0.321,respectively,P were 0.0094,0.0325 and 0.0361 respectively ) Between the pregnant group and non-pregnant group,the zinc and copper concentration in follicular fluid was not significantly different ( P ＞ 0.05 ) ; the serum estradiol ( E2 ) on the day of hCG administration was of significantly different(t =2.177,P =0.0353 );the serum zinc concentration on the day of hCG administration was of significantly different ( t =2.153,P =0.0372).Conclusion Trace elements zinc and copper might play an important role in the process of IVF-ET.
