CAJ | 학술논문

讨论骨纤维结构不良的病因及治疗方法.本文报道16例8岁以下幼儿期骨纤维结构不良,大部分为单灶性,发生于长骨骨干,研究其临床、X线、组织学表现和组织培养及各种治疗方法.经6个月～12年(6.2年)随访,治愈13例,复发率70%.骨纤维结构不良病变组织增生活跃、复发率高,浸润性生长,具有真性肿瘤特征.同时还根据病变纤维组织增生和化生骨化等病理过程的差别,将该病分为静止型和进展型.幼儿期骨纤维结构不良更具增生活性,多为进展型,应积极处理.
토론골섬유결구불량적병인급치료방법.본문보도16례8세이하유인기골섬유결구불량,대부분위단조성,발생우장골골간,연구기림상、X선、조직학표현화조직배양급각충치료방법.경6개월～12년(6.2년)수방,치유13례,복발솔70%.골섬유결구불량병변조직증생활약、복발솔고,침윤성생장,구유진성종류특정.동시환근거병변섬유조직증생화화생골화등병리과정적차별,장해병분위정지형화진전형.유인기골섬유결구불량경구증생활성,다위진전형,응적겁처리.
Objective:To study the etiology and treatment of fibrous dysplasia in children.Method:16 cases of fibrous dysplasia in children younger than 8 years are reported.Most of them were monostotic and the lesions located in the shaft of the long bone.The pathology,clinical manifestations,X-ray films,histology,tissue cultures and treatment were reviewed and analysed.The follow-up ranging from 6 mos to 12yrs(6yrs and 2mos in an average)showed that 13 cases of recurrence making a relapse rate of 70%.Results:Pathological sections of fibrous dysplasia showed true tumor's characters with active proliferation and infiltrative growth.The disease can be divided into resting type and developing type according to the degree of the proliferation and osseous metaplasia of the fibrous tissue.Conclusion:It is believed that the developing type of fibrous dysplasia should he treated surgically as early as possible.