国际泌尿系统杂志
國際泌尿繫統雜誌
국제비뇨계통잡지
INTERNATIONAL JOURNAL OF UROLOGY AND NEPHROLOGY
2011年
5期
631-633
,共3页
肾肿瘤%嗜酸细胞
腎腫瘤%嗜痠細胞
신종류%기산세포
Kidney Neoplasms%Eosubophils
目的 探讨肾嗜酸细胞瘤的诊断和治疗。方法 回顾分析12例肾嗜酸细胞瘤患者的临床资料，结合文献资料复习讨论。结果 男9例，女3例，年龄46～78岁，平均62岁。肿瘤直径2.0 ～9.2cm，平均5.4cm。1例以无痛肉眼血尿2周入院，余11例均为体检发现。CT扫描2例可见中央星芒状低密度影。肿瘤边界清楚，切面呈棕黄色，质地均匀，无出血及坏死灶。光镜下肿瘤细胞呈圆形或类圆形，细胞均匀一致，胞质内含有许多嗜酸性颗粒，细胞无明显异型性和核分裂相，免疫组化：Cytokeratin(+)、EAM(+)、Vimentin( -)。结论肾嗜酸细胞瘤是一种良性实质性上皮肿瘤，临床表现无特异性，影像学检查可帮助诊断，确诊需要病理行免疫组化检查，治疗以保留肾单位手术(NSS)为宜，术后密切随访。
目的 探討腎嗜痠細胞瘤的診斷和治療。方法 迴顧分析12例腎嗜痠細胞瘤患者的臨床資料，結閤文獻資料複習討論。結果 男9例，女3例，年齡46～78歲，平均62歲。腫瘤直徑2.0 ～9.2cm，平均5.4cm。1例以無痛肉眼血尿2週入院，餘11例均為體檢髮現。CT掃描2例可見中央星芒狀低密度影。腫瘤邊界清楚，切麵呈棕黃色，質地均勻，無齣血及壞死竈。光鏡下腫瘤細胞呈圓形或類圓形，細胞均勻一緻，胞質內含有許多嗜痠性顆粒，細胞無明顯異型性和覈分裂相，免疫組化：Cytokeratin(+)、EAM(+)、Vimentin( -)。結論腎嗜痠細胞瘤是一種良性實質性上皮腫瘤，臨床錶現無特異性，影像學檢查可幫助診斷，確診需要病理行免疫組化檢查，治療以保留腎單位手術(NSS)為宜，術後密切隨訪。
목적 탐토신기산세포류적진단화치료。방법 회고분석12례신기산세포류환자적림상자료，결합문헌자료복습토론。결과 남9례，녀3례，년령46～78세，평균62세。종류직경2.0 ～9.2cm，평균5.4cm。1례이무통육안혈뇨2주입원，여11례균위체검발현。CT소묘2례가견중앙성망상저밀도영。종류변계청초，절면정종황색，질지균균，무출혈급배사조。광경하종류세포정원형혹류원형，세포균균일치，포질내함유허다기산성과립，세포무명현이형성화핵분렬상，면역조화：Cytokeratin(+)、EAM(+)、Vimentin( -)。결론신기산세포류시일충량성실질성상피종류，림상표현무특이성，영상학검사가방조진단，학진수요병리행면역조화검사，치료이보류신단위수술(NSS)위의，술후밀절수방。
Objectives To study the diagnosis and treatment of renal oncocytoma. Methods Twelve cases of renal oncocytoma were reported here and the literatures were reviewed. Results 9 males,3 females, aged 46 ～ 78 years, mean 62 years. Tumor diameter 2.0 ～ 9.0cm, mean 5.4cm. One case was found because of painless gross hematuria 2 weeks. Other 11 cases were found by medical examination. CT scan shows 2 cases of central starshaped low - density shadow. The tumor were well - circumscribed, homogeneous and brown in color without haemorrhage and necrosis. On light microscopy, there was strong eosinophilic cytoplasm with granules, the tumor cells being tubular or no mitosis. The immunohistochemical staining was positive for Cytokeratin and EMA, whereas negative for Vimentin. Conclusions Renal oncocytoma is a type of benign, parenchymatous tumor, and it has no specific clinical feature. Imaging can help the diagnosis. The diagnosis can be established on histopathologic, immunohistochemical tests. Nephron sparing surgery(NSS) is the first choice treatment. Follow up is essential.
