CAJ | 학술논문

以肿瘤血管靶向分子(多肽、抗体和配体)为载体,以截短组织因子为效应分子的选择性诱发肿瘤血管血栓栓塞的抗肿瘤治疗是一种新颖的肿瘤血管靶向策略.本文就其临床前研究进展、治疗原理、治疗评价,3类肿瘤血管靶向治疗的区别、影响因素以及现存问题等作一综述.
이종류혈관파향분자(다태、항체화배체)위재체,이절단조직인자위효응분자적선택성유발종류혈관혈전전새적항종류치료시일충신영적종류혈관파향책략.본문취기림상전연구진전、치료원리、치료평개,3류종류혈관파향치료적구별、영향인소이급현존문제등작일종술.
Selective thrombosis in tumor vessels is a novel tumor vessel targeting strategy, which uses the tumor vessel targeting molecules (peptide,antibody,and ligand) as carriers,and truncated tissue factor as effector molecule. This paper reviews the progress of its preclinical studies,treatment principles, treatment evaluation,difference of three types of tumor vessel targeting therapy, influencing factors, and existing problems.