CAJ | 학술논문

目的调查福建省碘缺乏病高危地区新发地方性克汀病(简称地克病)、地方性甲状腺肿流行现况及防治措施落实情况,为制订有针对性的防治策略措施提供科学依据.方法 2010年,在碘盐监测覆盖率较低的秀屿区、翔安区、平潭县、东山县各抽取3个乡(镇),进行10岁以下新发地克病病例搜索；在每个乡(镇)抽取2所小学,每所小学抽取40名8～ 10岁儿童进行甲状腺B超检查,同时采集尿样,用砷铈催化分光光度法测定尿碘；在小学所在村抽取20名18 ～40岁育龄妇女,采集食用盐样和尿样,用半定量法测定盐碘,砷铈催化分光光度法测定尿碘.结果病例搜索未发现新发地克病及疑似地克病病例；8 ～ 10岁儿童总体甲状腺肿大率为3.6％ (37/1027),但东山县为5.4％( 13/240),超过国家消除碘缺乏病标准(＜5％)；8～10岁儿童和18～40岁育龄妇女的尿碘中位数分别为175.3、152.7 μg/L；碘盐覆盖率为82.7％ (382/462).结论福建省碘缺乏病高危地区未发现新发地克病及疑似地克病病例,人群尿碘中位数处于适宜水平.
목적 조사복건성전결핍병고위지구신발지방성극정병(간칭지극병)、지방성갑상선종류행현황급방치조시락실정황,위제정유침대성적방치책략조시제공과학의거.방법 2010년,재전염감측복개솔교저적수서구、상안구、평담현、동산현각추취3개향(진),진행10세이하신발지극병병례수색；재매개향(진)추취2소소학,매소소학추취40명8～ 10세인동진행갑상선B초검사,동시채집뇨양,용신시최화분광광도법측정뇨전；재소학소재촌추취20명18 ～40세육령부녀,채집식용염양화뇨양,용반정량법측정염전,신시최화분광광도법측정뇨전.결과 병례수색미발현신발지극병급의사지극병병례；8 ～ 10세인동총체갑상선종대솔위3.6％ (37/1027),단동산현위5.4％( 13/240),초과국가소제전결핍병표준(＜5％)；8～10세인동화18～40세육령부녀적뇨전중위수분별위175.3、152.7 μg/L；전염복개솔위82.7％ (382/462).결론 복건성전결핍병고위지구미발현신발지극병급의사지극병병례,인군뇨전중위수처우괄의수평.
Objective To investigate the occurrence of new cretinism cases and the prevalence of endemic goiter in iodine deficiency disorders(IDD) high-risk areas of Fujian province,so as to put forward target prevention and control measures for these areas.Methods Twelve counties from Xiuyu,Xiangan,Pingtan,and Dongshan were chosen into the survey by simple random sampling,searching for new cretinism cases were carried out in children under 10 years old.Two schools were chosen in every county and the thyroid volume of forty children aged 8 - 10 were determined by B-ultrasonography methods and their urinary iodine(UI) was determined by As3--Ce4+catalytic spectrophotometry in each school.Twenty women of child-bearing age aged 18 - 40 were chosen for collecting edible salt and urine samples,and the salt iodine content was determined using self-quantitative kit and their UI was also determined by As3--Ce4+ catalytic spectrophotometry.Results In the 4 high-risk counties,no cretinism cases were found.The goiter rate of children aged 8 - 10 was 3.6％(37/1027),and that in Dongshan county was 5.4％(13/240),which was higher than the national standards for eliminating IDD( ＜ 5％).The median urinary iodine(MUI) of children aged 8 - 10 was 175.3 μg/L,and the MUI of women aged 18 -40 was 152.7 μg/L.The coverage rate of iodized salt was 82.7％(382/462).Conclusions New case or suspected new case of cretinism is not discovered in the high-risk areas of IDD of Fujian province,and median urinary iodine level of people is in the adequate range.