CAJ | 학술논문

肺癌患者凝血纤溶系统改变在肿瘤的生物学特性、侵袭、远处转移和预后方面都有独特影响。肺癌患者的病理性高凝状态以及纤溶系统通过各种机制发挥的效应均与肿瘤预后直接相关，尤其是尿激酶型纤溶酶原激活物系统的改变，不仅有望成为肿瘤治疗新的突破点，更是预后的重要影响因素。
폐암환자응혈섬용계통개변재종류적생물학특성、침습、원처전이화예후방면도유독특영향。폐암환자적병이성고응상태이급섬용계통통과각충궤제발휘적효응균여종류예후직접상관，우기시뇨격매형섬용매원격활물계통적개변，불부유망성위종류치료신적돌파점，경시예후적중요영향인소。
In lung cancer patients, the changes of coagulation and fibrinolysis system have a special influence on the biological characteristics, invasion, metastasis and prognosis of tumer cells. Both pathological hypercoagulability and the effects produced by the urokinase plasminogen activator system through various mechanisms have direct relations with the prognosis in lung cancer patients. Especially,the urokinase plasminogen activator system is expected to be a new breakthrough in theropy and an important prognotic factor.