白介素4在支气管哮喘发病机制中的作用及其靶向治疗研究
백개소4재지기관효천발병궤제중적작용급기파향치료연구
Function and targeted therapy of interleukin-4 in bronchial asthma
  • 万方数据
    国际呼吸杂志 국제호흡잡지
    INTERNATIONAL JOURNAL OF RESPIRATION
    2011年 9期 691-695 ,共5页

    杨学敏%史海广%成家军%李志奎

    양학민%사해엄%성가군%리지규

    哮喘%白介素4%靶向治疗 哮喘%白介素4%靶嚮治療
    효천%백개소4%파향치료
    Asthma%Interleukin-4%Targeted therapy
    支气管哮喘(简称哮喘)发病率正逐年上升,其发病机制十分复杂.目前认为Th1/Th2反应失衡导致Th2细胞增多是其重要的发病机制之一,其中Th2细胞产生的细胞因子白介素4在哮喘发病中起重要的作用,成为新的哮喘治疗靶点.
    지기관효천(간칭효천)발병솔정축년상승,기발병궤제십분복잡.목전인위Th1/Th2반응실형도치Th2세포증다시기중요적발병궤제지일,기중Th2세포산생적세포인자백개소4재효천발병중기중요적작용,성위신적효천치료파점.
    The incidence of bronchial asthma (asthma) is increasing year by year, besides, the pathogenesis is very complex. Nowadays, it is believed that imbalance of Th1/Th2 response leading to excessively create of Th2 cells is one of the important pathogenesis. IL-4 produced by Th2 cells play an important role in asthma, understanding IL-4 in asthma may lead to new target to therapy in the future.
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