CAJ | 학술논문

目的观察860 MHz微波电磁辐射对痕迹性和延迟性眨眼条件反射双任务豚鼠模型的影响。方法采用抽签法将24只已建立双任务模型的豚鼠随机分为辐射1h组、辐射20 min组、假辐射组和正常对照组，每组6只。辐射1h组和辐射20 min组豚鼠头部接受频率为860 MHz、功率密度为1.0 mW/cm2的电磁辐射，每日1次，每次分别辐射1h和20 min，连续3d，假辐射组和正常对照组豚鼠不进行辐射，辐射结束后各组均进行眨眼条件反射训练。结果与正常对照组豚鼠相比，辐射1h组豚鼠的痕迹性和延迟性眨眼条件反射的习得率、峰幅度有明显下降(P＜0.05)，潜伏期无明显变化（P＞0.05），辐射20 min组、假辐射组和正常对照组的行为学参数均无明显变化(P＞0.05)。结论 860 MHz、1.0 mW/cm2、持续1h的微波电磁辐射可以使豚鼠眨眼条件反射两种任务的习得率和峰幅度均有显著下降，对豚鼠的学习记忆能力有影响。
목적 관찰860 MHz미파전자복사대흔적성화연지성잡안조건반사쌍임무돈서모형적영향。방법 채용추첨법장24지이건립쌍임무모형적돈서수궤분위복사1h조、복사20 min조、가복사조화정상대조조，매조6지。복사1h조화복사20 min조돈서두부접수빈솔위860 MHz、공솔밀도위1.0 mW/cm2적전자복사，매일1차，매차분별복사1h화20 min，련속3d，가복사조화정상대조조돈서불진행복사，복사결속후각조균진행잡안조건반사훈련。결과 여정상대조조돈서상비，복사1h조돈서적흔적성화연지성잡안조건반사적습득솔、봉폭도유명현하강(P＜0.05)，잠복기무명현변화（P＞0.05），복사20 min조、가복사조화정상대조조적행위학삼수균무명현변화(P＞0.05)。결론 860 MHz、1.0 mW/cm2、지속1h적미파전자복사가이사돈서잡안조건반사량충임무적습득솔화봉폭도균유현저하강，대돈서적학습기억능력유영향。
Objective To observe the effects of 860 MHz microwave radiation on an established dual task model of trace and delay eyeblink conditioning in guinea pigs.Methods Twenty-four guinea pigs with an established dual task model of trace and delay eyeblink conditioning were assigned randomly into four groups : a microwave-exposed 1 h group, a microwave-exposed 20 min group, a sham-exposed group and a normal control group.The guinea pigs in the 1 h and 20 min groups were irradiated on the head daily for 3 days using 860 MHz electromagnetic radiation at a power density of 1 mW/cm2 for 1 h and for 20 min, respectively. After radiation the guinea pigs were trained with classical dual task eyeblink conditioning.Results Compared with the normal control group, the behavioral parameters (acquisition rate and peak amplitude of trace and delay eyeblink) of guinea pigs in the microwave-exposed 1 h group had decreased significantly with no obvious change in latency. The behavioral parameters of guinea pigs in the microwave-exposed 20 min group, the sham-exposed group and the normal control group showed no obvious change.Conclusions Microwave radiation at 860 MHz and 1.0 mW/cm2 for 1 h can cause changes in dual trace and delay eyeblink conditioning in guinea pigs and decrease learning and memory capacity.