CAJ | 학술논문

目的探讨体外授精-胚胎移植患者子宫动脉血流和子宫内膜血流参数与妊娠结局的关系.方法行体外授精-胚胎移植的不孕症患者90例,均于注射绒毛膜促性腺激素(HCG)日应用三维能量多普勒超声测量子宫内膜厚度、内膜容积以及内膜血流参数.根据其妊娠与否分为妊娠组(43例,包括生化妊娠和临床妊娠)和非妊娠组(47例),比较两组之间参数的差异.结果两组间子宫动脉搏动指数(PI)、阻力指数(RI)值及内膜体积比较差异无统计学意义(P＞0.05)；内膜血管指数(VI)、血流指数(FI)和血管-血流指数(VFI)比较差异有统计学意义(P＜0.05).VI、FI、VFI的曲线下面积分别为0.880、0.713和0.646.其中VI的曲线下面积最大,VI的截断值为0.733％时,敏感性为84.2％,特异性为88.9％.结论在注射HCG日经阴道三维能量多普勒测量子宫内膜血流参数能较好地评价子宫内膜血流,预测妊娠结局.
목적 탐토체외수정-배태이식환자자궁동맥혈류화자궁내막혈류삼수여임신결국적관계.방법 행체외수정-배태이식적불잉증환자90례,균우주사융모막촉성선격소(HCG)일응용삼유능량다보륵초성측양자궁내막후도、내막용적이급내막혈류삼수.근거기임신여부분위임신조(43례,포괄생화임신화림상임신)화비임신조(47례),비교량조지간삼수적차이.결과 량조간자궁동맥박동지수(PI)、조력지수(RI)치급내막체적비교차이무통계학의의(P＞0.05)；내막혈관지수(VI)、혈류지수(FI)화혈관-혈류지수(VFI)비교차이유통계학의의(P＜0.05).VI、FI、VFI적곡선하면적분별위0.880、0.713화0.646.기중VI적곡선하면적최대,VI적절단치위0.733％시,민감성위84.2％,특이성위88.9％.결론 재주사HCG일경음도삼유능량다보륵측양자궁내막혈류삼수능교호지평개자궁내막혈류,예측임신결국.
Objective To evaluate whether endometrial blood flow measured by three-dimensional power Doppler ultrasound can predict pregnacy after the treatment of in vitro fertilization and embryo transfer (IVF-ET).Methods Ninty women who received the treatment of IVF-ET examined by threedimensional power Doppler imaging at the day of inject human chorionic gonadotropin(HCG) were enrolled.All patients were divided into pregnancy group (43 cases,include biochemical pregnancy and clinical pregnancy ) and non-pregnancy group(47 cases).The diagnostic value of parameters derived from threedimensional power Doppler imaging was evaluated by using the receiver operating characteristic (ROC)curve.Results Differences of these parameters,including vascularization index (VI),flow index(Fl) and vascularization flow index (VFI) were considered statistically significant between two groups,the parameters of uterine artery and endometrial volume had no significant differences between two groups.The area under ROC curve of VI,FI and VFI were 0.880,0.713 and 0.646,respectively.Among these parameters,VI had the highest diagnostic value for discriminating between benign and malignant endometrium,the cut-off value of which was 0.733 with a sensitivity of 84.2％.Conclusions Threedimensional power Doppler ultrasound was useful for evaluating endometrial blood flow in IVF-ET cycles.Endometrial blood flow parameters may be useful predictors for pregnancy.