中国医药
中國醫藥
중국의약
CHINA MEDICINE
2008年
8期
500-501
,共2页
陈炳锦%葛亚娟%朱芳%朱丽均%陈亚萍
陳炳錦%葛亞娟%硃芳%硃麗均%陳亞萍
진병금%갈아연%주방%주려균%진아평
外阴、阴道假丝酵母茵病%苦参凝胶%克霉唑
外陰、陰道假絲酵母茵病%苦參凝膠%剋黴唑
외음、음도가사효모인병%고삼응효%극매서
Vulvovaginal candidiasis%Gelatin kushen: Clotrimzde
目的 探讨克霉唑联合苦参凝胶治疗重度外阴、阴道假丝酵母茵病的临床治疗效果和药物不良反应.方法 98例外阴、阴道假丝酵母茵病患者采用随机单盲方法,分为克霉唑组34例、苦参凝胶组33例、克霉唑加苦参凝胶组31例,治疗后7d和月经后5d评估治疗效果.结果 克霉唑组临床治愈率和真菌清除率稍高于苦参凝胶组,但无统计学意义(P＞0.05),克霉唑加苦参凝胶组在治疗后第7天和月经后第5天均明显优于其他2组(P＜0.05).3组治疗耐受性好且均无严重药物不良反应发生.结论 克霉唑与苦参凝胶联合应用显著提高治疗效果,在治疗过程中未见严重局部和全身的药物不良反应,值得临床推广.
目的 探討剋黴唑聯閤苦參凝膠治療重度外陰、陰道假絲酵母茵病的臨床治療效果和藥物不良反應.方法 98例外陰、陰道假絲酵母茵病患者採用隨機單盲方法,分為剋黴唑組34例、苦參凝膠組33例、剋黴唑加苦參凝膠組31例,治療後7d和月經後5d評估治療效果.結果 剋黴唑組臨床治愈率和真菌清除率稍高于苦參凝膠組,但無統計學意義(P＞0.05),剋黴唑加苦參凝膠組在治療後第7天和月經後第5天均明顯優于其他2組(P＜0.05).3組治療耐受性好且均無嚴重藥物不良反應髮生.結論 剋黴唑與苦參凝膠聯閤應用顯著提高治療效果,在治療過程中未見嚴重跼部和全身的藥物不良反應,值得臨床推廣.
목적 탐토극매서연합고삼응효치료중도외음、음도가사효모인병적림상치료효과화약물불량반응.방법 98예외음、음도가사효모인병환자채용수궤단맹방법,분위극매서조34례、고삼응효조33례、극매서가고삼응효조31례,치료후7d화월경후5d평고치료효과.결과 극매서조림상치유솔화진균청제솔초고우고삼응효조,단무통계학의의(P＞0.05),극매서가고삼응효조재치료후제7천화월경후제5천균명현우우기타2조(P＜0.05).3조치료내수성호차균무엄중약물불량반응발생.결론 극매서여고삼응효연합응용현저제고치료효과,재치료과정중미견엄중국부화전신적약물불량반응,치득림상추엄.
Objective To evaluate the therapeutic effect and safety of gelatin Kushen in the treatment of severe vulvovaginal candidiasis.Methotis Ninty.eight patients of severe vulvovaginal candidiasis were treated randomly with clotrimazole,gelatin Kushen or elotrimazole combined with gelatin Kushen.The therapeutic effect and adverse reaction were observed at 7 days after treatment and 5 days after menstruation.Results The effective rates were similar between elotrimazole and gelatin Kushen(P＞0.05).Compared with single drug.the effective rate of clotrimazole combined with gelatin Kushen wal5 significantly increased(P＜0.05).No adverse reaction Was found.Conclusion Clotrimazole combined with gelatin Kushen was effective and safe in the treatment of severe v'ulvovaginal candidiasis.
