中华健康管理学杂志
中華健康管理學雜誌
중화건강관이학잡지
CHINESE JOURNAL OF HEALTH MANAGEMENT
2012年
2期
75-80
,共6页
戚文威%黄建凤%李建新%李莹%陈纪春%刘小清%赵连成%刘冬华%俞玲%吴先萍%阮连生%顾东风
慼文威%黃建鳳%李建新%李瑩%陳紀春%劉小清%趙連成%劉鼕華%俞玲%吳先萍%阮連生%顧東風
척문위%황건봉%리건신%리형%진기춘%류소청%조련성%류동화%유령%오선평%원련생%고동풍
饮酒%代谢综合征X%队列研究%发病率
飲酒%代謝綜閤徵X%隊列研究%髮病率
음주%대사종합정X%대렬연구%발병솔
Alcohol consumption%Metabolic syndrome X%Cohort studies%Incidence
目的 研究我国成年人饮酒状况对代谢综合征(MS)发病的影响.方法 本项目为前瞻性队列研究.2007至2008年对分别于1998和2000年基线调查的中国心血管病流行病学多中心协作研究35 ～ 74岁的27020例队列人群开展随访调查.结果 基线14572例非MS人群经8年随访,共发生MS 2362例.在调整了年龄、南北方、城乡、受教育程度、体力活动、吸烟、体质指数以及MS组分数后,和不饮酒者相比,男性饮酒者发生MS的相对危险度(RR)为1.24(95％ CI:1.06～1.45),人群归因危险度为10.13％；每日摄入酒精量10.1～20 g,20.1～40 g,＞40 g组的RR分别为1.36(95％CI:1.02～ 1.82),1.34(95％ CI:1.03～ 1.74)和1.41 (95％CI:1.13,～1.77)；每周饮酒2～5次和≥6次的RR分别为1.25(95％CI:1.01～ 1.55)和1.26(95％CI:1.04～ 1.52)；只喝啤酒组、只喝白酒组和混合饮酒组的RR分别为1.60(95％ CI:1.05～2.45)、1.30(95％CI:1.02～ 1.65)和1.27(95％CI:1.06 ～ 1.52).女性每日摄人酒精量在10.1 ～20 g组和＞20g组RR分别为2.67(95％CI:1.26～5.65)和2.38(95％CI:1.35～4.22).结论 在全人群中,每日摄入酒精量＞10 g就会显著增加MS发病风险,在女性中尤为明显.男性每周饮酒≥2次以及只饮啤酒、只饮白酒和混合饮酒者均明显升高MS的发病风险.为减少MS的流行,应提倡限制酒精过量摄入,尤其女性更应限制酒精摄入量(≤10 g/d).
目的 研究我國成年人飲酒狀況對代謝綜閤徵(MS)髮病的影響.方法 本項目為前瞻性隊列研究.2007至2008年對分彆于1998和2000年基線調查的中國心血管病流行病學多中心協作研究35 ～ 74歲的27020例隊列人群開展隨訪調查.結果 基線14572例非MS人群經8年隨訪,共髮生MS 2362例.在調整瞭年齡、南北方、城鄉、受教育程度、體力活動、吸煙、體質指數以及MS組分數後,和不飲酒者相比,男性飲酒者髮生MS的相對危險度(RR)為1.24(95％ CI:1.06～1.45),人群歸因危險度為10.13％；每日攝入酒精量10.1～20 g,20.1～40 g,＞40 g組的RR分彆為1.36(95％CI:1.02～ 1.82),1.34(95％ CI:1.03～ 1.74)和1.41 (95％CI:1.13,～1.77)；每週飲酒2～5次和≥6次的RR分彆為1.25(95％CI:1.01～ 1.55)和1.26(95％CI:1.04～ 1.52)；隻喝啤酒組、隻喝白酒組和混閤飲酒組的RR分彆為1.60(95％ CI:1.05～2.45)、1.30(95％CI:1.02～ 1.65)和1.27(95％CI:1.06 ～ 1.52).女性每日攝人酒精量在10.1 ～20 g組和＞20g組RR分彆為2.67(95％CI:1.26～5.65)和2.38(95％CI:1.35～4.22).結論 在全人群中,每日攝入酒精量＞10 g就會顯著增加MS髮病風險,在女性中尤為明顯.男性每週飲酒≥2次以及隻飲啤酒、隻飲白酒和混閤飲酒者均明顯升高MS的髮病風險.為減少MS的流行,應提倡限製酒精過量攝入,尤其女性更應限製酒精攝入量(≤10 g/d).
목적 연구아국성년인음주상황대대사종합정(MS)발병적영향.방법 본항목위전첨성대렬연구.2007지2008년대분별우1998화2000년기선조사적중국심혈관병류행병학다중심협작연구35 ～ 74세적27020례대렬인군개전수방조사.결과 기선14572례비MS인군경8년수방,공발생MS 2362례.재조정료년령、남북방、성향、수교육정도、체력활동、흡연、체질지수이급MS조분수후,화불음주자상비,남성음주자발생MS적상대위험도(RR)위1.24(95％ CI:1.06～1.45),인군귀인위험도위10.13％；매일섭입주정량10.1～20 g,20.1～40 g,＞40 g조적RR분별위1.36(95％CI:1.02～ 1.82),1.34(95％ CI:1.03～ 1.74)화1.41 (95％CI:1.13,～1.77)；매주음주2～5차화≥6차적RR분별위1.25(95％CI:1.01～ 1.55)화1.26(95％CI:1.04～ 1.52)；지갈비주조、지갈백주조화혼합음주조적RR분별위1.60(95％ CI:1.05～2.45)、1.30(95％CI:1.02～ 1.65)화1.27(95％CI:1.06 ～ 1.52).녀성매일섭인주정량재10.1 ～20 g조화＞20g조RR분별위2.67(95％CI:1.26～5.65)화2.38(95％CI:1.35～4.22).결론 재전인군중,매일섭입주정량＞10 g취회현저증가MS발병풍험,재녀성중우위명현.남성매주음주≥2차이급지음비주、지음백주화혼합음주자균명현승고MS적발병풍험.위감소MS적류행,응제창한제주정과량섭입,우기녀성경응한제주정섭입량(≤10 g/d).
Objective To examine the relationship between alcohol consumption and the incidence of metabolic syndrome (MS) in Chinese adults.Methods A total of 27020 Chinese adults aged 35 to 74years were enrolled in this prospective cohort study.Frequency or type of alcohol consunption was assessed in 1998 and 2000.Follow-up study on MS was conducted during 2007 and 2008.Results Over an average 8years' follow-up,2362 MS patients were identified among 14 572 individuals who did not have MS at baseline.After adjustment for age,location,education level,physical activity,cigarette smoking,body mass index and the number of MS components,compared with non-drinkers,relative risk ( RR ( 95％ confidence interval (CI))) and the Population Attributable Risk Percent (PARP) of MS of male drinkers was 1.24( 1.06 to 1.45 ) and 10.13％,respectively.RR (95 ％ CI) of MS was 1.36 ( 1.02 to 1.82 ),1.34 ( 1.03 to 1.74) and 1.41 (1.13 to 1.77) for male drinkers consuming alcohol 10.1 -20 g/d,20.1 -40 g/d,and ＞40 g/d.RR(95％ CI) of MS was 1.25 ( 1.01 to 1.55) for males drinking 2 -5 times/week and 1.26(1.04 to 1.52) for males drinking ≥6 times/week.RR (95％ CI) of MS was 1.60 ( 1.05 to 2.45),1.30(1.02 to 1.65) and 1.27 (1.06 to 1.52) for beer,liquor and the beer + liquor male consumers.The corresponding RR(95％ CI) was 2.67(1.26 to 5.65) and 3.38 (1.35 to 4.22) for female drinkers consuming alcohol 10.1 -20 g/d and ＞20 g/d.Conclusions Drinking alcohol more than 10 g/d may be associated with an increasing risk of MS,especially for women.Drinking more than twice per week,beer and/or liquor consumption can significantly increase the risk of MS in men.
