CAJ | 학술논문

目的探讨应用茶碱治疗毛细支气管炎的临床效果.方法将2005年2月至2006年5月住院治疗的毛细支气管炎患儿128例随机分为试验组和对照组,并根据病情区分为轻症和重症.对照组患儿按传统方案治疗,试验组患儿除传统方案治疗外,同时口服茶碱控释片治疗;入院当天、住院第3天、第7天分别测肺功能、气道α1-酸性糖蛋白、血白细胞介素-8和气道分泌物细胞计数及分类.结果试验组患儿肺功能及气道分泌物细胞计数及分类较对照组患儿明显改善.气道α1-酸性糖蛋白及血白细胞介素-8较对照组患儿明显降低,试验组轻症、重症患儿治愈率均高于对照组患儿.结论口服茶碱能减轻气管炎能改善肺功能,减轻小气道阻塞,提高治愈率.
목적 탐토응용다감치료모세지기관염적림상효과.방법 장2005년2월지2006년5월주원치료적모세지기관염환인128례수궤분위시험조화대조조,병근거병정구분위경증화중증.대조조환인안전통방안치료,시험조환인제전통방안치료외,동시구복다감공석편치료;입원당천、주원제3천、제7천분별측폐공능、기도α1-산성당단백、혈백세포개소-8화기도분비물세포계수급분류.결과 시험조환인폐공능급기도분비물세포계수급분류교대조조환인명현개선.기도α1-산성당단백급혈백세포개소-8교대조조환인명현강저,시험조경증、중증환인치유솔균고우대조조환인.결론 구복다감능감경기관염능개선폐공능,감경소기도조새,제고치유솔.
Objective To explore whether theophylline has clinic effects of treatment on bronchiolitis in children. Methods 128 children with bronchiolitis in our hospital were divided into the experiment and the control at random, in the meantime, grouped into the severe and the mild according to their condition. The children in the control were used traditional methods. The children in the control were taken theophylline, as well as used traditional methods. All patients in our hospital were checked up pulmonary function, alkyladenine glycosylase in trachea secretion, serum interleukin 8, cytotaxonomy in trachea secretion on time, after the third day and the 7th day. Results The pulmonary function and cytotaxonomy of the patients in the experiment were more improvement than that of the control. Their alkyladeniue gtycosylase in trachea secretion and serum interleukin 8 were very lower than that of the control. The cure rate in the mild and the severe of the experi-ment were higher than that of the control. Conclusion Administrating theophyUine by oral can improve the pulmonary function, relax a block of the small trachea, and raise the cure rate of patients with bronchiolitis.