国际脑血管病杂志
國際腦血管病雜誌
국제뇌혈관병잡지
INTERNATIONAL JOURNAL OF CEREBROVASCULAR DISEASES
2011年
4期
245-249
,共5页
周瑜%王景周%张莉莉%方传勤%高长越%杨清武%李敬诚
週瑜%王景週%張莉莉%方傳勤%高長越%楊清武%李敬誠
주유%왕경주%장리리%방전근%고장월%양청무%리경성
卒中%脑梗死%血栓溶解疗法%支架%组织型纤溶酶原激活剂%治疗结果
卒中%腦梗死%血栓溶解療法%支架%組織型纖溶酶原激活劑%治療結果
졸중%뇌경사%혈전용해요법%지가%조직형섬용매원격활제%치료결과
Stroke%Brain infarction%Thrombolytic therapy%Stents%Tissue plasminogen activator%Treatment outcome
目的 观察动脉溶栓辅助血管内支架成形术治疗急性脑梗死的效果.方法 采用前瞻性病例对照设计,将24例动脉溶栓后遗留血管狭窄(＞50%)的急性脑梗死患者分为支架治疗组和药物治疗组,分别给予支架成形术+药物治疗和常规药物治疗,评价两组血管完全再通率、残余狭窄率以及3个月时改良Rankin量表评分.结果 支架治疗组血管完全再通率高于药物治疗组(54.5%对0%,χ2=6.382,P＜0.001),残余狭窄率显著低于药物治疗组(4.5%±5.2%对82.5%±10.5%,t=7.464,P＜0.001),临床转归良好率显著高于药物治疗组(100%对76.9%,χ2=14.263,P=0.038).结论 动脉溶栓辅助血管内支架治疗急性脑梗死疗效优于药物治疗组,且较为安全.
目的 觀察動脈溶栓輔助血管內支架成形術治療急性腦梗死的效果.方法 採用前瞻性病例對照設計,將24例動脈溶栓後遺留血管狹窄(＞50%)的急性腦梗死患者分為支架治療組和藥物治療組,分彆給予支架成形術+藥物治療和常規藥物治療,評價兩組血管完全再通率、殘餘狹窄率以及3箇月時改良Rankin量錶評分.結果 支架治療組血管完全再通率高于藥物治療組(54.5%對0%,χ2=6.382,P＜0.001),殘餘狹窄率顯著低于藥物治療組(4.5%±5.2%對82.5%±10.5%,t=7.464,P＜0.001),臨床轉歸良好率顯著高于藥物治療組(100%對76.9%,χ2=14.263,P=0.038).結論 動脈溶栓輔助血管內支架治療急性腦梗死療效優于藥物治療組,且較為安全.
목적 관찰동맥용전보조혈관내지가성형술치료급성뇌경사적효과.방법 채용전첨성병례대조설계,장24례동맥용전후유류혈관협착(＞50%)적급성뇌경사환자분위지가치료조화약물치료조,분별급여지가성형술+약물치료화상규약물치료,평개량조혈관완전재통솔、잔여협착솔이급3개월시개량Rankin량표평분.결과 지가치료조혈관완전재통솔고우약물치료조(54.5%대0%,χ2=6.382,P＜0.001),잔여협착솔현저저우약물치료조(4.5%±5.2%대82.5%±10.5%,t=7.464,P＜0.001),림상전귀량호솔현저고우약물치료조(100%대76.9%,χ2=14.263,P=0.038).결론 동맥용전보조혈관내지가치료급성뇌경사료효우우약물치료조,차교위안전.
Objective To investigate the efficacy of intra-arterial thrombolysis with stenting for acute cerebral infarction. Methods Using a prospective case-control design, 24 patients with acute cerebral infarction who remained angiostegnosis ( ＞ 50%) after intra-arterial thrombolysis were randomly divided into stent treatment group and drug treatment group. They were treated with stenting + drug treatment and conventional drug treatment. The rates of vascular complete revascularization and residual stenosis, and the modified Rankin scale scores at 3 months in both groups were evaluated. Results The rate of complete revascularization in the stent treatment group was significantly higher than that in the drug treatment group (54. 5% vs.0%,χ2 =6.382, P ＜0. 001), and the rate of residual stenosis was significantly lower than that in the drug treatment group ([4.5 ±5.2]% vs. [82. 5 ±10. 5]%, t =7.464, P＜0.001). The rate of favorable clinical outcome in the stent treatment group was significantly higher than that in the drug treatment group (100% vs. 76. 9%,χ2 = 14. 263, P = 0.038). Conclusion The efficacy of intra-arterial thrombolysis with stenting in the treatment of acute cerebral infarction is superior to that in the drug treatment group, and it is safer.
