CAJ | 학술논문

背景硫化氢(hydrogen sulphide,H2S)是人们发现的第3个内源性气体信号转导分子,参与了许多疾病的发生发展过程,并且发现H2S相关药物对于某些疾病治疗取得了较为满意的结果.目的总结H2S在中枢神经系统、心血管系统等的作用以及相关机制.内容从中枢神经系统、心血管系统、呼吸系统、消化系统、炎症反应以及其他作用等方面综述近几年来对H2S研究的最新进展,发现H2S可能成为探求病因的一个新方向以及研发相关药物的可能性.趋向随着对H2S认识的加深,H2S相关药物有望成为一种临床用药.
배경 류화경(hydrogen sulphide,H2S)시인문발현적제3개내원성기체신호전도분자,삼여료허다질병적발생발전과정,병차발현H2S상관약물대우모사질병치료취득료교위만의적결과.목적 총결H2S재중추신경계통、심혈관계통등적작용이급상관궤제.내용 종중추신경계통、심혈관계통、호흡계통、소화계통、염증반응이급기타작용등방면종술근궤년래대H2S연구적최신진전,발현H2S가능성위탐구병인적일개신방향이급연발상관약물적가능성.추향 수착대H2S인식적가심,H2S상관약물유망성위일충림상용약.
Background Hydrogen sulphide (H2S) is the third endogenous gas signal transduction molecule at present,which involved in the development and progression of many diseases. Fairly satisfactory achievement of H2S-related drugs for treatment of certain diseases can be found.Objective To summary the role and related mechanism of hydrogen sulphide in the central nervous system,cardiovascular system et al.Content The review will focus on the latest research on H2S in the central nervous system,cardiovascular system,respiratory system,digestive system,inflammation and other aspect. H2S may be found in a new direction to explore the origin of a disease,and contribute to the possibility of studying new drugs.Trend With the deepening understanding of hydrogen sulfide,H2S-related drugs is expected to be used for clinical application.