CAJ | 학술논문

目的:通过颈动脉内-中膜厚度(Intima-media thickness,IMT)和肱动脉内皮依赖性扩张功能(Endothelium-dependen dilation,EDD)的检测,探讨围手术期疼痛与绝经期妇女血管内皮功能的关系.方法:采用B型超声检测围手术期绝经期女性上腹手术患者30名,测定手术前与手术后颈动脉内-中膜厚度和肱动脉内皮依赖性扩张功能;手术前后疼痛视觉模拟评分.结果:围手术期,绝经期女性颈动脉内-中膜平均厚度(0.78±0.37)mm;麻醉苏醒后(意识指令性恢复,自动性睁眼,抬头>5 s)2 h肱动脉内皮依赖性扩张功能为5.2%±1.0%,较手术前6.2%±1.5%有统计学差异(P<0.05);麻醉苏醒后2 h疼痛视觉模拟评分4.9±2.7较手术前1.03±1.9有统计学差异(P<0.00 1),且肱动脉内皮依赖性扩张功能的改变与疼痛刺激有独立相关性(r=0.868,P=0.032).结论:围手术期手术疼痛与绝经期女性的血管内皮功能的降低有密切关系.
목적:통과경동맥내-중막후도(Intima-media thickness,IMT)화굉동맥내피의뢰성확장공능(Endothelium-dependen dilation,EDD)적검측,탐토위수술기동통여절경기부녀혈관내피공능적관계.방법:채용B형초성검측위수술기절경기녀성상복수술환자30명,측정수술전여수술후경동맥내-중막후도화굉동맥내피의뢰성확장공능;수술전후동통시각모의평분.결과:위수술기,절경기녀성경동맥내-중막평균후도(0.78±0.37)mm;마취소성후(의식지령성회복,자동성정안,태두>5 s)2 h굉동맥내피의뢰성확장공능위5.2%±1.0%,교수술전6.2%±1.5%유통계학차이(P<0.05);마취소성후2 h동통시각모의평분4.9±2.7교수술전1.03±1.9유통계학차이(P<0.00 1),차굉동맥내피의뢰성확장공능적개변여동통자격유독립상관성(r=0.868,P=0.032).결론:위수술기수술동통여절경기녀성적혈관내피공능적강저유밀절관계.
Objective:To investigate the intima-media thickness(IMT) of carotid artery and endothelium-dependent dilation (EDD),and evaluate the relationship between pain and arterial endothelium function on menopause women during preopertion. Methods: The IMT and EDD in 30 menopause women were measuring by using B-mode ultrasound, pre-operatively and post-operatively;The visual analogue score (VSA) were mead pre-operatively and post-operatively. Results:IMT on carotid artery was(0.78±0.37 )mm;EDD(5.2%±1.0%) at 2 hour after recovery from anesthesia was significantly lower than pre-operative EDD (6.2%±1.5%)(P<0.05).VSA (4.9±2.7) at 2 hour after recovery from anesthesia was significantly lower than pre-operative VSA (1.03±1.9)(P<0.001).Dependent relations existed between EDD and pains(r=0.868,.P=0.032).Conclusion: This is significant relationship between pain and arterial endothelium function in menopause women during preopertion.