CAJ | 학술논문

对33例NGT、30例IGT和30例T2DM应用超声测量其肱动脉内径(DBA),计算收缩期血压由200mmHg降为0时DBA增大所代表的内皮依赖性血管舒张功能(EDF);测定可溶性选择素P和其他指标.结果显示:(1)EDF值,T2DM组低于IGT和NGT组,IGT组低于NGT组,差异有统计学意义.(2)IGT与T2DM组均显示:EDF值与HOMA-IR及可溶性选择素P呈显著负相关.
대33례NGT、30례IGT화30례T2DM응용초성측량기굉동맥내경(DBA),계산수축기혈압유200mmHg강위0시DBA증대소대표적내피의뢰성혈관서장공능(EDF);측정가용성선택소P화기타지표.결과 현시:(1)EDF치,T2DM조저우IGT화NGT조,IGT조저우NGT조,차이유통계학의의.(2)IGT여T2DM조균현시:EDF치여HOMA-IR급가용성선택소P정현저부상관.
The study of subjects with NGT(n=33),IGT(n=30)and T2DM(n=30) was completed by ultrasound-measuring the inner diameter of branchial artery (D-BA) and calculating the D-BA augment change as endothelium-dependent vasodilatation function(EDF,%) after SBP 200 mmHg to zero of rapid decompression,and by assaying sP-selectin and other parameters. The results showed that (1)EDF was lower in DM vs IGT vs NGT(7.6±3.3 vs 10.5±45 vs 13.1±4.9% separately,P<0.05),and lower in IGT vs NGT(P<0.05);(2)EDF was negatively related with HOMA-IR and sP-selectin (r=-0.57,-0.45,all P<0.01) in IGT and T2DM.