中国组织工程研究与临床康复
中國組織工程研究與臨床康複
중국조직공정연구여림상강복
JOURNAL OF CLINICAL REHABILITATIVE TISSUE ENGINEERING RESEARCH
2007年
44期
8997-9000
,共4页
王国华%孔祥泉%姜立民%张通%王葵光%孙军%王萍
王國華%孔祥泉%薑立民%張通%王葵光%孫軍%王萍
왕국화%공상천%강립민%장통%왕규광%손군%왕평
脊髓圆锥%腰椎%磁共振成像%测量
脊髓圓錐%腰椎%磁共振成像%測量
척수원추%요추%자공진성상%측량
背景:以往对成人脊髓圆锥末端位置的研究多限于尸体解剖且年代久远,因此有必要通过磁共振成像对国内人群的脊髓圆锥位置进行活体动态系列观察.目的:通过磁共振成像观察无脊柱脊髓畸形的脊髓圆锥位置的变化.设计:观察对比实验.单位:青岛市市立医院.对象:选择1993-10/2006-12青岛市市立医院放射科磁共振室收治的1199例因下腰痛进行腰椎磁共振成像检查的患者,男765例,女434例,年龄5~85岁,平均(46±14)岁.其中椎体转移性肿瘤或脊柱创伤276例,排除脊柱侧弯或先天性脊柱脊髓疾病患者.另选择30名健康志愿者到院健康体检者,男女各15名,年龄19~52岁,平均(32±8)岁.所有受试对象均对检测项目知情同意.方法:应用美国GE公司Signa 1.5T磁共振成像机对1199例患者行腰椎磁共振扫描,自旋回波T1加权、正中矢状位像上观测脊髓圆锥末端的位置.根据其与相应椎体的上、中、下1/3及椎间盘的对应关系定位.另对30例健康志愿者进行了腰椎中立、过屈、过伸位脊髓圆锥末端的动态观察.主要观察指标:下腰痛患者脊髓圆锥末端的位置及健康志愿者不同脊髓体位圆锥末端的动态观察结果.结果:下腰痛患者1 199例及30名健康志愿者均进入结果分析.①下腰痛患者脊髓圆锥末端的平均位置为L1的下1/3水平(范围:T12的中1/3~L3的上1/3),圆锥末端的位置呈正态分布,女性圆锥位置低于男性(t=18.127,P<0.01),各年龄段无差别(F=0.530,P>0.05).②当脊椎过伸或过屈位时,圆锥位置相对于椎体后缘上下关系无变化,但过屈时略接近椎体后缘,过伸时略远离椎体后缘.结论:本组人群中脊髓圆锥末端的位置位于T12的中1/3~L3的上1/3,女性圆锥位置低于男性.
揹景:以往對成人脊髓圓錐末耑位置的研究多限于尸體解剖且年代久遠,因此有必要通過磁共振成像對國內人群的脊髓圓錐位置進行活體動態繫列觀察.目的:通過磁共振成像觀察無脊柱脊髓畸形的脊髓圓錐位置的變化.設計:觀察對比實驗.單位:青島市市立醫院.對象:選擇1993-10/2006-12青島市市立醫院放射科磁共振室收治的1199例因下腰痛進行腰椎磁共振成像檢查的患者,男765例,女434例,年齡5~85歲,平均(46±14)歲.其中椎體轉移性腫瘤或脊柱創傷276例,排除脊柱側彎或先天性脊柱脊髓疾病患者.另選擇30名健康誌願者到院健康體檢者,男女各15名,年齡19~52歲,平均(32±8)歲.所有受試對象均對檢測項目知情同意.方法:應用美國GE公司Signa 1.5T磁共振成像機對1199例患者行腰椎磁共振掃描,自鏇迴波T1加權、正中矢狀位像上觀測脊髓圓錐末耑的位置.根據其與相應椎體的上、中、下1/3及椎間盤的對應關繫定位.另對30例健康誌願者進行瞭腰椎中立、過屈、過伸位脊髓圓錐末耑的動態觀察.主要觀察指標:下腰痛患者脊髓圓錐末耑的位置及健康誌願者不同脊髓體位圓錐末耑的動態觀察結果.結果:下腰痛患者1 199例及30名健康誌願者均進入結果分析.①下腰痛患者脊髓圓錐末耑的平均位置為L1的下1/3水平(範圍:T12的中1/3~L3的上1/3),圓錐末耑的位置呈正態分佈,女性圓錐位置低于男性(t=18.127,P<0.01),各年齡段無差彆(F=0.530,P>0.05).②噹脊椎過伸或過屈位時,圓錐位置相對于椎體後緣上下關繫無變化,但過屈時略接近椎體後緣,過伸時略遠離椎體後緣.結論:本組人群中脊髓圓錐末耑的位置位于T12的中1/3~L3的上1/3,女性圓錐位置低于男性.
배경:이왕대성인척수원추말단위치적연구다한우시체해부차년대구원,인차유필요통과자공진성상대국내인군적척수원추위치진행활체동태계렬관찰.목적:통과자공진성상관찰무척주척수기형적척수원추위치적변화.설계:관찰대비실험.단위:청도시시립의원.대상:선택1993-10/2006-12청도시시립의원방사과자공진실수치적1199례인하요통진행요추자공진성상검사적환자,남765례,녀434례,년령5~85세,평균(46±14)세.기중추체전이성종류혹척주창상276례,배제척주측만혹선천성척주척수질병환자.령선택30명건강지원자도원건강체검자,남녀각15명,년령19~52세,평균(32±8)세.소유수시대상균대검측항목지정동의.방법:응용미국GE공사Signa 1.5T자공진성상궤대1199례환자행요추자공진소묘,자선회파T1가권、정중시상위상상관측척수원추말단적위치.근거기여상응추체적상、중、하1/3급추간반적대응관계정위.령대30례건강지원자진행료요추중립、과굴、과신위척수원추말단적동태관찰.주요관찰지표:하요통환자척수원추말단적위치급건강지원자불동척수체위원추말단적동태관찰결과.결과:하요통환자1 199례급30명건강지원자균진입결과분석.①하요통환자척수원추말단적평균위치위L1적하1/3수평(범위:T12적중1/3~L3적상1/3),원추말단적위치정정태분포,녀성원추위치저우남성(t=18.127,P<0.01),각년령단무차별(F=0.530,P>0.05).②당척추과신혹과굴위시,원추위치상대우추체후연상하관계무변화,단과굴시략접근추체후연,과신시략원리추체후연.결론:본조인군중척수원추말단적위치위우T12적중1/3~L3적상1/3,녀성원추위치저우남성.
BACKGROUND:Studies on the tip position of the conus medullaris in a population have been limited to autopsy and long ago. Therefore, it is necessary to dynamically study the position of conus medullaris (CM) in the Chinese population by magnetic resonance imaging (MRI).OBJECTIVE: To observe the variation in position of the CM in a living population without spinal deformity through MRI. DESIGN: A controlled observation.SETTING: Qingdao Municipal Hospital.PARTICIPANTS: Totally 1199 patients who complained of low back pain and underwent MRI examination in the Department of Radiology of Qingdao Municipal Hospital between October 1993 and December 2006 were recruited in this study. The involved patients, including 765 males and 434 females, were averaged (46±14)years ranging from 5 to 85 years old. Among them, 276 patients suffered from metastatic tumor on spinal vertebrae or trauma of spinal column. Patients with scoliosis or congenital diseases of spinal cord and spinal column were rejected. Another 30 volunteers were recruited via advertisement checked up in the Department of Radiology of Qingdao Municipal Hospital.All the volunteers, including 15 males and 15 females, were averaged (32±8)years, ranging from 19 to 52 years.Written informed consents of detected items were obtained from all the subjects.METHODS: Totally 1199 patients underwent lumbar vertebra MRI scanning by a GE Signa 1.5T supraconduction MRI machine. The tip position of the conus medullaris was observed by spin echo T1 weighted and median sagittal imaging.The MRI machine was located according to its corresponding relationship with vertebral body and intervertebral disc. All the volunteers were given the dynamic research conceming the tip of CM in middle, hyperflexion and hyperextension position.MAIN OUTCOME MEASURES: Dynamic observation of the location of tip of CM in the healthy volunteers and the patients who complained of low back pain.RESULTS: The above 1199 patients who complained of low back pain and 30 healthy volunteers participated in the final analysis. ①The mean conus position of the patients who complained of low back pain was the lower third of L1 (range: middle third of T12 to upper third of L3). The variation in conus positions followed a normal distribution. The conus position in female patients was significantly lower than that of male counterparts (t =18.127,P < 0.01). No significant difference in conus position was seen with increasing age (F =0.530, P > 0.05). ②The tip of the CM did not change in relation to the posterior edge of vertebrae when the spine was in hyperflexion or hyperextension position.However, it got close slightly to the posterior edge of vertebrae when in hyperflexion, and got away slightly from it when in hyperextension.CONCLUSION: The location of tip of CM of our group of population ranges from the middle third of T12 to the upper third of L3, and female population have a much lower conus position than that of male ones.