CAJ | 학술논문

目的　评价99mTc-甲氧基异丁基异腈（MIBI）显像鉴别乳房肿块良恶性的价值。　方法　对1 06例乳房肿块行99mTc-MIBI显像检查，全部病例均经手术治疗，与病理结果比较。　结果　106例中乳腺癌56例，显像阳性4 8例，假阴性主要为肿块较小的乳腺癌；良性病变50例，显像阴性40例，假阳性主要为血供丰富的大纤维腺瘤。该法诊断乳腺癌的灵敏度为85.7％、特异性为80.0％、阳性预告值82 .8％、阴性预告值83.3%、总正确诊断率为83.0%。　结论　99mTc-MIBI显像是鉴别乳房良恶性肿块的有效的、无创性检查方法，但对大纤维腺瘤和较小的恶性肿块诊断作用较差。
목적　평개99mTc-갑양기이정기이정（MIBI）현 상감별유방종괴량악성적개치。　방법　대1 06례유방종괴행99mTc-MIBI현상검사，전부병례균경수술치료，여병리결과비 교。　결과　106례중유선암56례，현상양성4 8례，가음성주요위종괴교소적유선암；량성병변50례，현상음성40례，가양성주요위혈공 봉부적대섬유선류。해법진단유선암적령민도위85.7％、특이성위80.0％、양성예고치82 .8％、음성예고치83.3%、총정학진단솔위83.0%。　결론　99mTc-MIBI현상시감별유방량악성종괴적유효적、무창성검 사방법，단대대섬유선류화교소적악성종괴진단작용교차。
Objective　To evaluate 99mTc-MI BI SPECT in differentiating malignancies from benign breast masses.　Methods　106 patients with palpable breast mas ses underwent the examination of 99mTc-MIBI SPECT. Tentative di agnosis was evaluated by postoperative pathology in all cases.　Results　48 of the 56 cases of breast carcinoma were preoperatively diagnosed by 99mTc-MIBI SPECT, 40 of the 50 pati ents with benign lesions were scintimammographically negative. The sensitivity of the examination was 85.7%, specificity was 80.0%, positive predictive value was 82.8%, negative predictive value was 83.3%, and the diagnostic accuracy w as 83.0%. False-positive results were found mainly in large fibroadenomas with abundant vascularities and false-negative results were mainly from some small malignant tumors.　Conclusions　9 9mTc-MIBI SPECT is an effective, noninvasive diagnostic method for primar y breast cancer. But its value is limited in detecting large fibroadenoma and sm all malignancy.