CAJ | 학술논문

顺-1-呋喃乙酰基-2-对位取代苯基-6,6-二甲基-5,7-二氧-螺-[2,5]-4,8-辛二酮和顺-1-噻吩乙酰基-2-对位取代苯基-6,6-二甲基-5,7-二氧-螺-[2,5]-4,8-辛二酮与甲醇于封管中80 ℃反应72 h得到β-呋喃甲酰基-γ-甲氧基-γ-对取代苯基-丁酸甲酯及β-噻吩甲酰基-γ-甲氧基-γ-对取代苯基-丁酸甲酯,其结构经1H NMR, 13C NMR, IR, MS及APT.讨论了反应机理.
순-1-부남을선기-2-대위취대분기-6,6-이갑기-5,7-이양-라-[2,5]-4,8-신이동화순-1-새분을선기-2-대위취대분기-6,6-이갑기-5,7-이양-라-[2,5]-4,8-신이동여갑순우봉관중80 ℃반응72 h득도β-부남갑선기-γ-갑양기-γ-대취대분기-정산갑지급β-새분갑선기-γ-갑양기-γ-대취대분기-정산갑지,기결구경1H NMR, 13C NMR, IR, MS급APT.토론료반응궤리.
Methyl β-furoyl-γ-p-substituted phenylbutyrates or methyl β-thienoyl-γ-p-substituted phenylbutyrates was synthesized by the reaction of 1,2,3-trisubstituted electron-deficient cyclopropane derivatives cis-1-furoyl-2-p-substituted phenyl-6,6-dimethyl-5,7-dioxa-spiro-[2,5]-4,8-octadiones or cis-1-thienoyl-2-p-substituted phenyl-6,6-dimethyl-5,7-dioxa-spiro-[2,5]-4,8-octadiones with methanol at 80 ℃ for 72 h in a sealed tube. The structures were confirmed by 1H NMR,13C NMR, IR, MS and APT. The reaction mechanism for the formation of the products was also proposed.