CAJ | 학술논문

目的研究棉团铁线莲Clematis hexapetala Pall.的干燥根及根茎的化学成分.方法利用溶剂提取,硅胶柱色谱和高效液相色谱等手段进行分离、纯化,根据理化性质和波谱数据进行结构鉴定.结果分离鉴定了12个黄酮类化合物,分别为:3, 5, 6, 7, 8, 3′, 4′ -七甲氧基黄酮(1), nobiletin (2), liquiritigenin (3), 橙皮素 (4),柚皮素(5),7, 4′ - 二羟基- 二氢黄酮-7-O-β-D -葡萄糖苷(6), 5, 7,4′ - 三羟基-3′ -甲氧基黄酮醇-7-O-α-L- 鼠李糖(1→6)-β-D-葡萄糖苷(7),6-hydroxybiochain A(8),芒柄花素(9),大豆素(10),染料木素(11),鸢尾苷(12).结论以上化合物均为首次从该植物中分离得到.
목적연구면단철선련Clematis hexapetala Pall.적간조근급근경적화학성분.방법이용용제제취,규효주색보화고효액상색보등수단진행분리、순화,근거이화성질화파보수거진행결구감정.결과분리감정료12개황동류화합물,분별위:3, 5, 6, 7, 8, 3′, 4′ -칠갑양기황동(1), nobiletin (2), liquiritigenin (3), 등피소 (4),유피소(5),7, 4′ - 이간기- 이경황동-7-O-β-D -포도당감(6), 5, 7,4′ - 삼간기-3′ -갑양기황동순-7-O-α-L- 서리당(1→6)-β-D-포도당감(7),6-hydroxybiochain A(8),망병화소(9),대두소(10),염료목소(11),연미감(12).결론이상화합물균위수차종해식물중분리득도.
Aim To study the chemical constituents from the roots and rhizomes of Clematis hexapetala Pall.. Methods The components were isolated by means of solvent extraction, repeated chromatography with silica gel, sephadex LH-20 and prep-HPLC. The structures were determined by spectrum analysis. Results　Twelve flavonoids were isolated and their structures were identified as 3, 5, 6, 7, 8, 3′, 4′ -heptamethoxyflavone (1), nobiletin (2), liquiritigenin (3), hesperetin (4), naringenin (5), liquiritigen-7-O-β-D-glucopyranoside (6), 5, 7, 4′ -trihydroxy-3′- methoxyflavanone -7-O-α-L-rhamnopyranosyl (1→6) -β-D-glucopyranoside (7), 6-hydroxybiochain A (8), formononetin (9), daidzein (10), genistein (11), and tectoridin (12). Conclusion　All the said compounds were isolated from the plant for the first time.