CAJ | 학술논문

目的探讨血红蛋白释放试验(HRT)与糖尿病的关系,观察血糖浓度对HRT的影响.方法取各种血糖浓度的血液标本,每例标本同时做全血和红细胞的HRT(应用梯带释放法),观察血糖浓度与HRT结果的关系.进一步进行体外试验,以研究葡萄糖对HRT的影响.结果全血HRT结果与血糖浓度无关.梯带释放与血糖浓度有一定的相关性.体外试验葡萄糖浓度对红细胞的梯带释放影响明显;葡萄糖能使梯带增强,且有按5%、10%、50%递增趋势.结论葡萄糖能影响红细胞的HRT,改变红细胞的通透性.
목적 탐토혈홍단백석방시험(HRT)여당뇨병적관계,관찰혈당농도대HRT적영향.방법 취각충혈당농도적혈액표본,매례표본동시주전혈화홍세포적HRT(응용제대석방법),관찰혈당농도여HRT결과 적관계.진일보진행체외시험,이연구포도당대HRT적영향.결과 전혈HRT결과 여혈당농도무관.제대석방여혈당농도유일정적상관성.체외시험포도당농도대홍세포적제대석방영향명현;포도당능사제대증강,차유안5%、10%、50%체증추세.결론 포도당능영향홍세포적HRT,개변홍세포적통투성.
Objective To explore the relationship between hemoglobin release test(HRT)and diabetes,and to know the effect of blood glucose on HRT.Methods 10 blood samples was take to do whole blood HRT and erythrocyte HRT(ladder release)simultaneously,analysis the relationship between the concentration of blood glucose and results of HRT.In vitro,the effect of blood glucose on HRT was studied.Results There did not exist relationship between whole blood HRT and blood glucose concentratlon. But Iadder release was associated with blood glucose concentration.In vitro,glucose concentration influenced the ladder release of erythrocyte.Glucose enhanced the ladder release with the trend of 5%、10%、50%.Conclusion Glucose could influence the erythrocyte HRT with changing the permeability of erythrocyte.