CAJ | 학술논문

目的探讨丝裂霉素C在泪囊鼻腔吻合术中的应用及效果。方法将92例105眼慢性泪囊炎随机分为MMC组48例55眼和对照组44例50眼，MMC组术中应用0.4g.L-1MMC，对照组未用MMC，术后平均随访29mo。结果手术成功率：MMC组为98.08%，对照组为82.61%(P＜0.05)。吻合口开通率：MMC组为100%，对照组为82.61%(P＜0.01)。前后瓣膜愈合时间：MMC组为7.86d±2.75d，对照组为7.22d±2.23d(P＞0.05)。吻合口出血发生率：MMC组为3.62%，对照组为2%.结论 MMC可作为治疗慢性泪囊炎的一种安全、简单、有效的辅助措施，明显提高手术成功率。
목적 탐토사렬매소C재루낭비강문합술중적응용급효과。방법 장92례105안만성루낭염수궤분위MMC조48례55안화대조조44례50안，MMC조술중응용0.4g.L-1MMC，대조조미용MMC，술후평균수방29mo。결과 수술성공솔：MMC조위98.08%，대조조위82.61%(P＜0.05)。문합구개통솔：MMC조위100%，대조조위82.61%(P＜0.01)。전후판막유합시간：MMC조위7.86d±2.75d，대조조위7.22d±2.23d(P＞0.05)。문합구출혈발생솔：MMC조위3.62%，대조조위2%.결론 MMC가작위치료만성루낭염적일충안전、간단、유효적보조조시，명현제고수술성공솔。
Objective To probeinto the application and effect of mitomycinC(MMC) to dacryocystorhinostomy.Methods The chronic dacryocystisis,92 cases(105 eyes)were performed with the same level dacryocystorhinostomy,randomly divided into two groups:MMC group,48 cases(55 eyes) given MMC 0.4g.L-1. Control group,44 cases (50 eyes) without MMC.The average period of postoperative following-up was 29 months.ResultsThe successful rates of remote operations: 98.08% in MMC group,82.61%(P＜0.05) in the control group.The percentage of anastomotic stoma open:100% in MMC group,82.61%(P＜0.01) in the control group. Healing period of anterior and posterior valve:7.86d±2.75 d in MMC group and 7.22d±2.23d(P＞0.05) in the control group.The bleeding ratio of anastomotic stoma:3.62% in MMC group, 2% in the control group.Conclusion MMC can be used as one of safe ,simple ,effective and auxiliary measures to treat chronic dacrocystisis,which can notably enhance the successful rates of operations.