CAJ | 학술논문

目的：从番荔枝科植物圆滑番荔枝（AnnonaglabraLinn.）树皮提取分离活性成分。方法：95%乙醇提取、溶剂萃取、硅胶柱层析、重结晶等。结果：分离到6个化合物，其中5个为贝壳杉烷型二萜，1个生物碱。5个二萜Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ分别为(-)-kaur-16-en-19-oicacid、16α-hydro-19-acetoxy-ent-kauran-17-oic acid、(-)-kauran-19-al-17-oic acid、ent-19-carbomethoxykauran-17-oicacid、19-hydroxy-16α-(-)-kauran-17-oic acid,生物碱为oxoglaucine。结论：萜Ⅳent-19-carbomethoxykauran-17-oicacid、萜Ⅴ19-hydroxy-16α-(-)-kauran-17-oic acid和生物碱oxoglaucine为首次从该植物中分得。
목적：종번려지과식물원활번려지（AnnonaglabraLinn.）수피제취분리활성성분。방법：95%을순제취、용제췌취、규효주층석、중결정등。결과：분리도6개화합물，기중5개위패각삼완형이첩，1개생물감。5개이첩Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ분별위(-)-kaur-16-en-19-oicacid、16α-hydro-19-acetoxy-ent-kauran-17-oic acid、(-)-kauran-19-al-17-oic acid、ent-19-carbomethoxykauran-17-oicacid、19-hydroxy-16α-(-)-kauran-17-oic acid,생물감위oxoglaucine。결론：첩Ⅳent-19-carbomethoxykauran-17-oicacid、첩Ⅴ19-hydroxy-16α-(-)-kauran-17-oic acid화생물감oxoglaucine위수차종해식물중분득。
AIM:Bio-active constituents were expected to be obtained fromAnnona glabra Linn. METHODS: It is extracted with 95% alcohol, distributed by different solvents, isolated via column chromatography on silica gel and purified by crystallization et al. RESULTS: Six compounds were isolated from Annona glabra Linn. Among them, five compounds were kaurane diterpenoids and one compound was alkaloid. On the basis of the preperties and spectral analysis, their structures were identified as terpeneⅠ(-)-kaur-16-en-19-oic acid、terpeneⅡ16α-hydro-19-acetoxy-ent-kauran-17-oic acid、terpeneⅢ(-)-kauran-19-al-17-oic acid、terpene Ⅳent-19-carbomethoxykauran-17-oic acid、terpeneⅤ 19-hydroxy-16α-(-)-kauran-17-oic acid and alkaloid oxoglaucine. CONCLUSION: Among them, ent-19-carbomethoxykauran-17-oic acid、19-hydroxy-16α-(-)-kauran-17-oic acid and oxoglaucine were isolated from this plant for the first time.