CAJ | 학술논문

目的：验证医用不锈钢316表面钽沉积后生物相容性的变化。方法：在医用不锈钢316表面进行钽沉积，之后将大鼠骨髓基质干细胞分别植入钽沉积表面和316基底表面，分别进行X射线衍射检测材料表面钽沉积量、两种材料表面细胞形态观测、细胞黏附率检测、碱性磷酸酶活性检测。结果：经X射线衍射检测钽有效的沉积于医用不锈钢316表面；细胞于两种材料表面生长良好；24 h细胞黏附率钽沉积表面高于316不锈钢表面（P<0.05）；经过5 d连续细胞培养，钽沉积材料表面大鼠骨髓基质干细胞的活性高于316不锈钢材料表面（P<0.05）。结论：316医用不锈钢经过钽沉积后其表面生物相容性高于其本来材料。
목적：험증의용불수강316표면단침적후생물상용성적변화。방법：재의용불수강316표면진행단침적，지후장대서골수기질간세포분별식입단침적표면화316기저표면，분별진행X사선연사검측재료표면단침적량、량충재료표면세포형태관측、세포점부솔검측、감성린산매활성검측。결과：경X사선연사검측단유효적침적우의용불수강316표면；세포우량충재료표면생장량호；24 h세포점부솔단침적표면고우316불수강표면（P<0.05）；경과5 d련속세포배양，단침적재료표면대서골수기질간세포적활성고우316불수강재료표면（P<0.05）。결론：316의용불수강경과단침적후기표면생물상용성고우기본래재료。
Objective:To verify the medical biocompatible surface changes of 316 stainless steel after tantalum deposition. Method:316 medical stainless steel after tantalum surface deposition,and then the rat bone marrow stromal cells were implanted tantalum deposition surface of the substrate surface and 316,respectively,the amount of material deposited tantalum surface were detected by X-ray diffraction,the surface morphology observation of two materials,cell adhesion attach rate detection,alkaline phosphatase activity were detected. Result:Detected by X-ray diffraction results tantalum effective deposition in 316 medical stainless steel surface;cells grew well in the surface of the two materials;24 h cell adhesion rate of tantalum deposition surface was higher than 316 stainless steel surfaces(P<0.05);through 5 d continuous cell culture ,tantalum deposition surface of rat bone marrow stromal stem cell activity was higher than the 316 stainless steel material(P<0.05). Conclusion:316 medical stainless steel surface after deposition of biocompatible tantalum is higher than its original material.