CAJ | 학술논문

目的对10例重叠综合征患者的临床和实验室资料综合分析，以了解重叠综合征患者的睡眠结构、肺功能、血气分析等改变特征，提高对该病的认识。方法 10例均经详细病史、查体、血气分析、血生化、血常规、肺功能、ECG、UCG、多导睡眠图及胸片等检查。结果 10例患者均有明显夜间低氧血症和严重的睡眠结构紊乱。其中5例经无创机械通气治疗夜间低氧和呼吸紊乱改善明显。结论 COPD和 SAS并存时，肺动脉高压、心功能不全的危险性增加，且COPD与SAS相互促进病程进展，因此早期诊断治疗是十分必要的。
목적대10례중첩종합정환자적림상화실험실자료종합분석，이료해중첩종합정환자적수면결구、폐공능、혈기분석등개변특정，제고대해병적인식。방법 10례균경상세병사、사체、혈기분석、혈생화、혈상규、폐공능、ECG、UCG、다도수면도급흉편등검사。결과 10례환자균유명현야간저양혈증화엄중적수면결구문란。기중5례경무창궤계통기치료야간저양화호흡문란개선명현。결론 COPD화 SAS병존시，폐동맥고압、심공능불전적위험성증가，차COPD여SAS상호촉진병정진전，인차조기진단치료시십분필요적。
Objectives　To evaluate the change of sleep structure，pulmonary function and blood gas analysis of overlap syndrome for 10 cases，to study of clinical and experimental characteristics.Methods　 10 patients received detail collection of case history、physical examination，blood gas analysis，pulmonary function and over night polysomonography monitoring et al.Results　 Sleep apnea hypopnea index as well as nocturnal hypoxemia were more obvious in overlap syndrome for 10 cases。5 patients were treated by nCPAP or BiPAP,their symptoms were reduced.Conclusions　 COPD with SAS were indicated higher risk of repirator hypertension and heart function failure.They could be develped for each other.It is necessary to deagnosis and therapy early.