CAJ | 학술논문

目的分析2009-2011年江苏省手足口病流行特征.方法从疾病监测信息报告管理系统中获取江苏省2009-2011年手足口病疫情资料,采用描述性流行病学以及时空重排扫描统计方法分析.结果 2009-2011年江苏省累计报告手足口病285 414例,年均发病率为122.66/10万,发病水平逐年增长；累计报告重症病例3686例,占报告病例总数的1.29％.病例主要分布在≤5岁年龄组,占病例总数的93.64％;总病例中散居儿童占64.08％,重症病例占78.65％.全省各地区发病均处于较高水平,年均发病率44.02/10万至202.90/10万；苏州、南京、无锡是最主要的高发地区,报告病例数约占全省病例总数的40％；大部分地区重症病例数均逐年增加,其中宿迁、盐城地区增长幅度最大,2011年较2010年分别增长了339.22％和328.33％.全年有2个发病高峰,最高峰出现在4-6月,次高峰出现在11月.在区县尺度上有时空聚集性,总病例探测到8个时空聚类区域,重症病例探测到7个时空聚类区域.3年来全省共报告实验室确诊病例12 359例,其中普通病例10414例,重症1945例.普通病例中肠道病毒71型(EV71)、柯萨奇病毒A16型(CoxA16)分别占43.49％和37.07％；重症病例中EV71占80.82％,其他肠道病毒占13.21％,CoxA16仅占5.96％.结论江苏省手足口病处于高度流行态势.≤5岁散居儿童是主要发病人群；苏南、苏北地区流行强度不同,且季节性变化规律存在差异；病原学构成以EV71、CoxA16为主,不同季节病原学构成存在差异.
목적 분석2009-2011년강소성수족구병류행특정.방법 종질병감측신식보고관리계통중획취강소성2009-2011년수족구병역정자료,채용묘술성류행병학이급시공중배소묘통계방법분석.결과 2009-2011년강소성루계보고수족구병285 414례,년균발병솔위122.66/10만,발병수평축년증장；루계보고중증병례3686례,점보고병례총수적1.29％.병례주요분포재≤5세년령조,점병례총수적93.64％;총병례중산거인동점64.08％,중증병례점78.65％.전성각지구발병균처우교고수평,년균발병솔44.02/10만지202.90/10만；소주、남경、무석시최주요적고발지구,보고병례수약점전성병례총수적40％；대부분지구중증병례수균축년증가,기중숙천、염성지구증장폭도최대,2011년교2010년분별증장료339.22％화328.33％.전년유2개발병고봉,최고봉출현재4-6월,차고봉출현재11월.재구현척도상유시공취집성,총병례탐측도8개시공취류구역,중증병례탐측도7개시공취류구역.3년래전성공보고실험실학진병례12 359례,기중보통병례10414례,중증1945례.보통병례중장도병독71형(EV71)、가살기병독A16형(CoxA16)분별점43.49％화37.07％；중증병례중EV71점80.82％,기타장도병독점13.21％,CoxA16부점5.96％.결론 강소성수족구병처우고도류행태세.≤5세산거인동시주요발병인군；소남、소북지구류행강도불동,차계절성변화규률존재차이；병원학구성이EV71、CoxA16위주,불동계절병원학구성존재차이.
Objective To analyze the epidemic characteristics of hand-foot-mouth disease (HFMD) in Jiangsu province.Methods We downloaded the case-data of HFMD in Jiangsu province during 2009-2011 from the Chinese National Notifiable Infectious Disease Reporting System,and made a comprehensive analysis on the epidemiological features of it with descriptive epidemiological methods and retrospective space-time permutation scan statistics.Results A total of 285 414 cases were reported in Jiangsu,from 2009 to 2011,with an annual incidence of 122.66 per 100 000.There were 3686 severe cases in the 3 years accumulatively,accounting for 1.29％ of the total.Proportion of the cases being 5 years old or even younger was 93.64％.Scatteredly living children accounted for 64.08％ of the total cases and 78.65％ of the severe cases,respectively.The epidemics of HFMD were visible in each city of Jiangsu province,with a lowest annual incidence rate of 44.02 per 100 000 and a highest one up to 202.90 per 100 000.Regions as Suzhou,Nanjing,Wuxi had the highest incidence in the province,with cases in these three areas occupying almost 40％ of all.The numbers of severe cases in Suqian and in Yancheng cities increased by 339.22％ and 328.33％ in 2011 compared to in 2010,respectively,and the rates of increase in these two cities were much higher than those in the other regions.Two peaks of incidence were observed every year,with the highest occurring between April and June and the second occurring in November.The spatial-temporal distribution of HFMD was not random in Jiangsu province,from 2009 to 2011.Clusters for general cases in August and 7 clusters for severe cases were detected,respectively.12 359 cases of HFMD were laboratory confirmed in the said 3 years,including 10 414 common cases and 1945 severe cases.EV71 and CoxA16 accounted for 43.49％ and 37.07％ of common cases,respectively.In terms of the severe cases,the ratios were 80.82％ and 5.96％,respectively.Conclusion HFMD was highly endemic in Jiangsu province,and the situation of prevention and control for it is still grim.Scatteredly living children of 5 years old or younger were the major population at risk,and the epidemic in different regions and seasons was different.EV71 and CoxA16 were the major etiologic agents,but the etiologic constitute showed seasonal changes.