CAJ | 학술논문

第一类抗冻蛋白分子上的苏氨酸或缬氨酸对其在冰晶表面的吸附起主要作用,在此观点的基础上,认为抗冻蛋白分子在冰晶表面的吸附依赖于这些氨基酸上的甲基与冰晶的van der Waals相互作用,从理论上计算了第一类抗冻蛋白分子与冰晶的相互作用能,给出了几种第一类抗冻蛋白分子与冰晶的相互作用能.计算结果与实验结果符合较好.
제일류항동단백분자상적소안산혹힐안산대기재빙정표면적흡부기주요작용,재차관점적기출상,인위항동단백분자재빙정표면적흡부의뢰우저사안기산상적갑기여빙정적van der Waals상호작용,종이론상계산료제일류항동단백분자여빙정적상호작용능,급출료궤충제일류항동단백분자여빙정적상호작용능.계산결과여실험결과부합교호.
Based on the viewpoint that the hydrophobic methyl groups on threonines or valines play the main roles for the binding mechanism of type I antifreeze proteins,it has been suggested that the adsorption of antifreeze proteins on the ice crystals is due to van der Waals interactions between these methyl groups and ice crystals,then the interaction energy between a type I antifreeze protein and an ice crystal is calculated theoretically,and it also gives the interaction energies of some mutants of a type I antifreeze protein and the ice.The calculation results are in good agreement with the experimental data.