生态毒理学报
生態毒理學報
생태독이학보
ASIAN JOURNAL OF ECOTOXICOLOGY
2012年
2期
220-224
,共5页
张农%刘海新%苏捷%叶孙忠%李庐峰
張農%劉海新%囌捷%葉孫忠%李廬峰
장농%류해신%소첩%협손충%리려봉
毒性%河豚毒素%织纹螺
毒性%河豚毒素%織紋螺
독성%하돈독소%직문라
toxicity%tetrodotoxin%Nassarius
对2002年福建省引起食物中毒的织纹螺毒素进行研究.高效液相色谱-质谱联用(liquid chromatography/mass,LC/MS)的分析结果显示,织纹螺毒素的主要成分是河豚毒素类毒素(tetrodotoxin,TTX),另外还含有4-epi TTX、anhydroTTX、deoxyTTX等成分.生物法对织纹螺毒素的毒力测定结果表明:所收集的26个织纹螺样品中15个检测出毒性,毒素的毒力在5.7 ~ 47.3MU·g-1之间.毒力最高的织纹螺样品2003年5月1日来自福安,主要由半褶织纹螺和另一未定种组成.
對2002年福建省引起食物中毒的織紋螺毒素進行研究.高效液相色譜-質譜聯用(liquid chromatography/mass,LC/MS)的分析結果顯示,織紋螺毒素的主要成分是河豚毒素類毒素(tetrodotoxin,TTX),另外還含有4-epi TTX、anhydroTTX、deoxyTTX等成分.生物法對織紋螺毒素的毒力測定結果錶明:所收集的26箇織紋螺樣品中15箇檢測齣毒性,毒素的毒力在5.7 ~ 47.3MU·g-1之間.毒力最高的織紋螺樣品2003年5月1日來自福安,主要由半褶織紋螺和另一未定種組成.
대2002년복건성인기식물중독적직문라독소진행연구.고효액상색보-질보련용(liquid chromatography/mass,LC/MS)적분석결과현시,직문라독소적주요성분시하돈독소류독소(tetrodotoxin,TTX),령외환함유4-epi TTX、anhydroTTX、deoxyTTX등성분.생물법대직문라독소적독력측정결과표명:소수집적26개직문라양품중15개검측출독성,독소적독력재5.7 ~ 47.3MU·g-1지간.독력최고적직문라양품2003년5월1일래자복안,주요유반습직문라화령일미정충조성.
Toxins in Nassarius gastropods during food intoxication event in Fujian Province in 2002 were studied.The toxin extracted from the gastropods was analyzed by high-performance liquid chromatography/mass spectrometry,and the result indicated that the toxin consisted of tetrodotoxin (TTX) and its derivatives,i.e,4-epiTTX,deoxyTTX,as well as anhydroTTX.The toxic equivalent of the toxins was also detected by the bioassay approach,and the results indicated that 15 gastropods were confirmed to be positive among 26 samples,the toxicity in samples ranged from 5.7 to 47.3 mouse units per gram (MU· g- 1).The gastropods with highest toxicity was collected from Fu'an on May 1,2003,which were consisted of two species,i.e.,Nassarius semiplicatus and a species not yet documented.