中国医药
中國醫藥
중국의약
CHINA MEDICINE
2010年
8期
755-757
,共3页
张剑锋%赵艇%魏东%葛雪燕
張劍鋒%趙艇%魏東%葛雪燕
장검봉%조정%위동%갈설연
痔%纳米银抗菌水凝胶
痔%納米銀抗菌水凝膠
치%납미은항균수응효
Hemorrhoids%Nanosilver antimicrobe hydrogel
目的 探讨纳米银抗菌水凝胶在治疗Ⅲ度、Ⅳ度内痔高频电容场痔疮治疗(HCPT)术后疗效的有效性及安全性.方法 筛选Ⅲ度、Ⅳ度内痔HCPT术后患者78例,采用随机数字表法将患者分为治疗组与对照组各39例,治疗组于术后第1天至第7天给予纳米银抗菌水凝胶早晚纳肛,1支/次,用药前均用温水清洗患处,对照组术后常规处理,如改善饮食、保持大便通畅、保持肛周清洁、温热坐浴等,不使用纳米银抗菌水凝胶.分别观察患者用药后48 h及第7 d疼痛、出血、水肿、分泌物、瘙痒等常见症状改善情况,并评价其疗效.结果 治疗组48 h疼痛、水肿、分泌物3项观察指标评分分别为(0.85±0.74)分、(0.90±0.71)分、(0.95±0.75)分,对照组分别为(2.80±0.41)分、(2.50±0.68)分、(2.25±0.72)分,;治疗组7 d水肿、瘙痒2项观察指标评分分别为(0.80±0.77)分、(0.60±0.68)分,对照组分别为(1.70±0.98)分、(1.80±0.95)分,差异均有统计学意义(P<0.05).治疗组7 d显效15例(38.5%)与对照组[6例(15.4%)]比较,差异有统计学意义(P<0.05).结论 纳米银抗菌水凝胶可缓解Ⅲ度、Ⅳ度内痔HCPT术后常见不适症状,疗效确切,安全性高.
目的 探討納米銀抗菌水凝膠在治療Ⅲ度、Ⅳ度內痔高頻電容場痔瘡治療(HCPT)術後療效的有效性及安全性.方法 篩選Ⅲ度、Ⅳ度內痔HCPT術後患者78例,採用隨機數字錶法將患者分為治療組與對照組各39例,治療組于術後第1天至第7天給予納米銀抗菌水凝膠早晚納肛,1支/次,用藥前均用溫水清洗患處,對照組術後常規處理,如改善飲食、保持大便通暢、保持肛週清潔、溫熱坐浴等,不使用納米銀抗菌水凝膠.分彆觀察患者用藥後48 h及第7 d疼痛、齣血、水腫、分泌物、瘙癢等常見癥狀改善情況,併評價其療效.結果 治療組48 h疼痛、水腫、分泌物3項觀察指標評分分彆為(0.85±0.74)分、(0.90±0.71)分、(0.95±0.75)分,對照組分彆為(2.80±0.41)分、(2.50±0.68)分、(2.25±0.72)分,;治療組7 d水腫、瘙癢2項觀察指標評分分彆為(0.80±0.77)分、(0.60±0.68)分,對照組分彆為(1.70±0.98)分、(1.80±0.95)分,差異均有統計學意義(P<0.05).治療組7 d顯效15例(38.5%)與對照組[6例(15.4%)]比較,差異有統計學意義(P<0.05).結論 納米銀抗菌水凝膠可緩解Ⅲ度、Ⅳ度內痔HCPT術後常見不適癥狀,療效確切,安全性高.
목적 탐토납미은항균수응효재치료Ⅲ도、Ⅳ도내치고빈전용장치창치료(HCPT)술후료효적유효성급안전성.방법 사선Ⅲ도、Ⅳ도내치HCPT술후환자78례,채용수궤수자표법장환자분위치료조여대조조각39례,치료조우술후제1천지제7천급여납미은항균수응효조만납항,1지/차,용약전균용온수청세환처,대조조술후상규처리,여개선음식、보지대편통창、보지항주청길、온열좌욕등,불사용납미은항균수응효.분별관찰환자용약후48 h급제7 d동통、출혈、수종、분비물、소양등상견증상개선정황,병평개기료효.결과 치료조48 h동통、수종、분비물3항관찰지표평분분별위(0.85±0.74)분、(0.90±0.71)분、(0.95±0.75)분,대조조분별위(2.80±0.41)분、(2.50±0.68)분、(2.25±0.72)분,;치료조7 d수종、소양2항관찰지표평분분별위(0.80±0.77)분、(0.60±0.68)분,대조조분별위(1.70±0.98)분、(1.80±0.95)분,차이균유통계학의의(P<0.05).치료조7 d현효15례(38.5%)여대조조[6례(15.4%)]비교,차이유통계학의의(P<0.05).결론 납미은항균수응효가완해Ⅲ도、Ⅳ도내치HCPT술후상견불괄증상,료효학절,안전성고.
Objective To evaluate the clinical efficacy and safety of nanosilver antimicrobe hydrogel in the treatment of Ⅲ° ,Ⅳ° internal hemorrhoids after high-freauency capacitance pile treatment ( HCPT). Methods Sev-enty-eight patients who received HCPT were randomly divided into study group with Nanosilver Antimicrobe Hydrogel ( n = 39 ) and control group without Nanosilver Antimicrobe Hydrogel ( n = 39 ) , the symptomatic relief including pain, bleeding, edema, percolate and pruritus was evaluated by scoring system at 48 hours,7d after HCPT. Results Score reduction on pain, edema and percolate [(0. 85 ± 0. 74) vs (2. 80 ± 0.41), (0. 90 ± 0. 71) vs ( 2. 50 ±0.68), (0.95 ± 0.75) vs (2. 25 ± 0. 72 )] was significantly different between the two groups after 48 hours (P <0.05). After 7-days treatment, score reduction on edema and pruritus was significantly different that in the study group than in the control group (P <0.05). But there was no significant difference in score on bleeding between two groups (P>0.05). The effective rat was significantly different between the study group than the control group(P<0.05). Conclusion Data from the study shows that nanosilver antimicrobe hydrogel is safe and effective in the treatment ofⅢ° , Ⅳ° internal hemorrhoids after HCPT.
