原子能科学技术
原子能科學技術
원자능과학기술
ATOMIC ENERGY SCIENCE AND TECHNOLOGY
2009年
z2期
404-406
,共3页
朱养妮%江新标%张强%张继红%陈伟%赵柱民
硃養妮%江新標%張彊%張繼紅%陳偉%趙柱民
주양니%강신표%장강%장계홍%진위%조주민
硼中子俘获治疗%吸收剂量%肿瘤
硼中子俘穫治療%吸收劑量%腫瘤
붕중자부획치료%흡수제량%종류
boron neutron capture therapy%absorbed dose%tumor
应用MCNP 4B程序模拟计算了硼中子俘获治疗(BNCT)人体头颅等效模型开颅时的宏观吸收剂量分布.采用含有肿瘤体的双椭球结构的等效模型,模拟了深部肿瘤、浅部肿瘤和表层肿瘤3个算例,计算了正常组织及肿瘤体内的宏观吸收剂量分布.计算结果表明,照射后部分网格的吸收剂量低于治疗标准18 Gy,但在同一网格中,肿瘤越靠近表层,吸收剂量越大,治疗效果越好.
應用MCNP 4B程序模擬計算瞭硼中子俘穫治療(BNCT)人體頭顱等效模型開顱時的宏觀吸收劑量分佈.採用含有腫瘤體的雙橢毬結構的等效模型,模擬瞭深部腫瘤、淺部腫瘤和錶層腫瘤3箇算例,計算瞭正常組織及腫瘤體內的宏觀吸收劑量分佈.計算結果錶明,照射後部分網格的吸收劑量低于治療標準18 Gy,但在同一網格中,腫瘤越靠近錶層,吸收劑量越大,治療效果越好.
응용MCNP 4B정서모의계산료붕중자부획치료(BNCT)인체두로등효모형개로시적굉관흡수제량분포.채용함유종류체적쌍타구결구적등효모형,모의료심부종류、천부종류화표층종류3개산례,계산료정상조직급종류체내적굉관흡수제량분포.계산결과표명,조사후부분망격적흡수제량저우치료표준18 Gy,단재동일망격중,종류월고근표층,흡수제량월대,치료효과월호.
The dose distribution in a equivalent model of head in the case of operation for boron neutron capture therapy was simulated with MCNP 4B code. In order to calculate the absorbed dose rate of healthy tissue and tumor cells in the head, it was simulated by a double-ellipsoid equivalent model of head loaded with a tumor. Three cases of deep tumor case, deeper tumor case and shallow tumor case were studied. The result indicates that the absorbed dose in some grids can not achieve the treat standard of 18 Gy with irradiation. While in the same grid, the tumor is shallower, the absorbed dose is bigger, and the curative effect is better.