国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2010年
15期
1846-1848
,共3页
急性脑梗死%同型半胱氨酸%神经元特异性烯醇化酶
急性腦梗死%同型半胱氨痠%神經元特異性烯醇化酶
급성뇌경사%동형반광안산%신경원특이성희순화매
Acute cerebral infarction%Homocysteine%Neuron-special enolas
目的 研究急性脑梗死(ACI)患者治疗前、后血清同型半胱氨酸(Hcy)和神经元特异性烯醇化酶(NSE)水平的变化与意义.方法 应用化学发光法和双抗体夹心ELISA法对120例ACI患者治疗前、后进行血清Hcy和NSE水平测定.结果 ACI患者治疗后血清Hcy(5.6±1.5)μmol/L,明显低于治疗前的(18.8±3.2)μmol/L及对照组的(7.5±1.5)μmol/L,比较差异有显著性(P＜0.05); ACI患者治疗后血清NSE(7.04±2.1)μg/L,明显低于治疗前的(21.06±4.6)μg/L,比较差异有显著性(P＜0.05).结论 检测ACI患者血清Hcy和NSE水平对判断病情和预后有重要价值.
目的 研究急性腦梗死(ACI)患者治療前、後血清同型半胱氨痠(Hcy)和神經元特異性烯醇化酶(NSE)水平的變化與意義.方法 應用化學髮光法和雙抗體夾心ELISA法對120例ACI患者治療前、後進行血清Hcy和NSE水平測定.結果 ACI患者治療後血清Hcy(5.6±1.5)μmol/L,明顯低于治療前的(18.8±3.2)μmol/L及對照組的(7.5±1.5)μmol/L,比較差異有顯著性(P＜0.05); ACI患者治療後血清NSE(7.04±2.1)μg/L,明顯低于治療前的(21.06±4.6)μg/L,比較差異有顯著性(P＜0.05).結論 檢測ACI患者血清Hcy和NSE水平對判斷病情和預後有重要價值.
목적 연구급성뇌경사(ACI)환자치료전、후혈청동형반광안산(Hcy)화신경원특이성희순화매(NSE)수평적변화여의의.방법 응용화학발광법화쌍항체협심ELISA법대120례ACI환자치료전、후진행혈청Hcy화NSE수평측정.결과 ACI환자치료후혈청Hcy(5.6±1.5)μmol/L,명현저우치료전적(18.8±3.2)μmol/L급대조조적(7.5±1.5)μmol/L,비교차이유현저성(P＜0.05); ACI환자치료후혈청NSE(7.04±2.1)μg/L,명현저우치료전적(21.06±4.6)μg/L,비교차이유현저성(P＜0.05).결론 검측ACI환자혈청Hcy화NSE수평대판단병정화예후유중요개치.
Objective To investigate the changes in serum levels of Hcy and Neuron-special enolas (NSE) after treatment in patients with acute cerebral infarction. Methods Serun Hcy levels were detected by chemiluminescence, and so were NSE levels by ELISA in 120 patients with cerebral infarction before and after treatment. Results Before treatment, serum levels of Hcy and NSE were significantly higher in the patients than in the healthy controls (P>0.05); and they were significantly diferent after treatment (P<0.05). Conclusions Detection of serum levels of Hcy and NSE plays an important role in estimating the disease course and predicting the prognosis
