CAJ | 학술논문

目的:通过调查中国四川省松潘县藏族成人脉压的分布特点,探讨藏族成人脉压异常与心血管病危险因素和心功能的相关性.方法:采用流行病学横断面的研究方法,对中国四川省松潘县18～74岁的1015名藏族成人的身体健康状况进行随机、分层、整群抽样问卷调查和体格检查.结果:四川松潘县藏族成人平均脉压是(45.59±14.22)mmHg,脉压异常的有143例(14.09%).多因素线性回归和Logistic回归分析结果显示:脉压异常与年龄呈正相关(OR=1.05,P<0.05),与高密度脂蛋白水平呈负相关(OR=-2.69,P<0.05).与正常脉压组相比,脉压异常组全身血管阻力(SVR)显著增加[(1112.61±346.74)kPa/L比(1308.27±354.87)kPa/L,t＝-4.87],每搏量指数(SI)[(45.68±12.76)ml/m2比(39.45±9.52)ml/m2,t=4.37]、心输出量指数(CI)[(3.55±1.00)L/min.m2比(3.22±0.54)L/min.m2,t=3.08]显著降低(P均<0.05).结论:中国四川省松潘县18～74岁藏族成人中脉压异常的比例较高.脉压异常与心血管病危险因素和心功能指标有关.对脉压异常藏族成人进行健康管理具有重要的公共卫生意义.
목적:통과조사중국사천성송반현장족성인맥압적분포특점,탐토장족성인맥압이상여심혈관병위험인소화심공능적상관성.방법:채용류행병학횡단면적연구방법,대중국사천성송반현18～74세적1015명장족성인적신체건강상황진행수궤、분층、정군추양문권조사화체격검사.결과:사천송반현장족성인평균맥압시(45.59±14.22)mmHg,맥압이상적유143례(14.09%).다인소선성회귀화Logistic회귀분석결과현시:맥압이상여년령정정상관(OR=1.05,P<0.05),여고밀도지단백수평정부상관(OR=-2.69,P<0.05).여정상맥압조상비,맥압이상조전신혈관조력(SVR)현저증가[(1112.61±346.74)kPa/L비(1308.27±354.87)kPa/L,t＝-4.87],매박량지수(SI)[(45.68±12.76)ml/m2비(39.45±9.52)ml/m2,t=4.37]、심수출량지수(CI)[(3.55±1.00)L/min.m2비(3.22±0.54)L/min.m2,t=3.08]현저강저(P균<0.05).결론:중국사천성송반현18～74세장족성인중맥압이상적비례교고.맥압이상여심혈관병위험인소화심공능지표유관.대맥압이상장족성인진행건강관리구유중요적공공위생의의.
Objective:To explore relation among abnormal pulse pressure (PP) and cardiovascular risk factors,cardiac function in Tibetan adults through survey on distributive characteristics of PP in Tibetan adults from Songpan county,Sichuan province in China.Methods:An crosssection study was carried out in Songpan county,Sichuan province of China.Questionnaire investigation and physical examination were performed by multiphase,stratified,unequal proportional and random cluster sampling to investigate 1015 Tibetan adults aged 18-74 years.Results: In Songpan county the average PP is (45.59±14.22)mmHg; the incidence rate of abnormal PP was 14.09％(143/1015).Multifactor linear regression and Logistic regression analysis showed that abnormal PP was positively related with age (OR=1.05,P<0.05) and negatively related with level of high density lipoprotein (OR=-2.69,P<0.05).Compare with normal PP group,systemic vascular resistance [SVR,(1112.61±346.74) kPa/L vs.(1308.27±354.87) kPa/L,t=-4.87] significantly increased,levels of cardiac index [CI,(3.55±1.00) L/min m2 vs.(3.22±0.54) L/min m2,t=3.08] and stroke index [SI,(45.68±12.76) ml/m2 vs.(39.45±9.52) ml/m2,t=4.37] significantly decreased in abnormal PP group (P<0.05 all).Conclusion:Abnormal PP is common in Chinese Tibetan adults aged 18～74 years,which associated with cardiovascular risk factors and change of cardiac function.Health management for Tibetan adults with abnormal PP is strongly advocated.