CAJ | 학술논문

目的评价前列腺按摩联合α1受体阻滞剂治疗Ⅲ型前列腺炎的疗效.方法将符合Ⅲ型前列腺炎诊断标准的86例患者随机分为治疗组及对照组,治疗组45例,给以每周2次的前列腺按摩及特拉唑嗪2 mg,每天1次.对照组41例仅给以特拉唑嗪2 mg,每天1次.疗程6周.采用美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)评分作为疗效评价指标评价两组疗效.结果 86例患者完成了6周的治疗并接受评估,治疗组患者治疗前后NIH-CPSI总分分别为(29.5 ±4.2)、(9.6±3.8)分,对照组治疗前后NIH-CPSI总分分别为(28.9±3.4)、(14.6±3.6)分,两组治疗前后相比总分下降均有统计学意义(t=12.131、6.999,均P＜0.05),治疗组总分下降幅度明显大于对照组(t=4.649,P＜0.05).治疗过程中无严重不良反应发生.结论前列腺按摩联合α1受体阻滞剂治疗能有效缓解Ⅲ型前列腺炎患者的症状,改善患者的生活质量.联合治疗疗效优于单用α1受体阻滞剂治疗.
목적 평개전렬선안마연합α1수체조체제치료Ⅲ형전렬선염적료효.방법 장부합Ⅲ형전렬선염진단표준적86례환자수궤분위치료조급대조조,치료조45례,급이매주2차적전렬선안마급특랍서진2 mg,매천1차.대조조41례부급이특랍서진2 mg,매천1차.료정6주.채용미국국립위생연구원만성전렬선염증상지수(NIH-CPSI)평분작위료효평개지표평개량조료효.결과 86례환자완성료6주적치료병접수평고,치료조환자치료전후NIH-CPSI총분분별위(29.5 ±4.2)、(9.6±3.8)분,대조조치료전후NIH-CPSI총분분별위(28.9±3.4)、(14.6±3.6)분,량조치료전후상비총분하강균유통계학의의(t=12.131、6.999,균P＜0.05),치료조총분하강폭도명현대우대조조(t=4.649,P＜0.05).치료과정중무엄중불량반응발생.결론 전렬선안마연합α1수체조체제치료능유효완해Ⅲ형전렬선염환자적증상,개선환자적생활질량.연합치료료효우우단용α1수체조체제치료.
Objective To observe the efficacy of prostatic massage combined with α1 receptor blocker in the treatment of type Ⅲ prostatitis. Methods 86 cases were randomly divided into two groups. The treatment group( n =45 ) were given twice-weekly prostatic massage in combination with α1 receptor blocker( terazosin 2mg per night) for 6 weeks. Thc control group(n =41 )were only given terazosin 2mg per night for 6 weeks. AII the patients were asked to complete the National Institutes of Healthe Chronic Prostatitis Symptom Index(NIH-CPSI) before and after the treatment. Results 86 cases were evaluated after the treatment. The NIH-CPSI scores of the two groups decreased from ( 29.5 ± 4.2 ) to ( 9.6 ± 3.8), from ( 28.9 ± 3.4) to ( 14.6 ± 3.6) respectively, with statistically significant differences from pretreatment( t = 12.131、6.999, all P ＜ 0.05 )as well as between the combined therapy group and the control group(t = 4.649, P ＜ 0.05). There were no serious side effects during the therapy. Conclusion Prostatic massage combined with α1 receptor blocker can relieve the symptoms in type Ⅲ prostatitis patients and improve their life quality. The combined therapy can produce better efficacy than terazosin used alone.