CAJ | 학술논문

目的观察文拉法辛合并舒必利治疗抑郁症的疗效和不良反应.方法对64例住院的抑郁症患者随机分为两组,研究组给予文拉法辛合并舒必利治疗,对照组单用文拉法辛治疗,采用汉密尔顿抑郁量表(HAMD)及副反应量表(TESS)评定疗效和不良反应.结果研究组第一周HAMD减分率33.08%显著高于对照组10.64%,四周后研究组显效率87.5%优于对照组68.8%,两组均无严重不良反应.结论文拉法辛合并舒必利能快速缓解抑郁症状,疗效优于单用文拉法辛,不良反应不增加,患者依从性好.
목적 관찰문랍법신합병서필리치료억욱증적료효화불량반응.방법 대64례주원적억욱증환자수궤분위량조,연구조급여문랍법신합병서필리치료,대조조단용문랍법신치료,채용한밀이돈억욱량표(HAMD)급부반응량표(TESS)평정료효화불량반응.결과 연구조제일주HAMD감분솔33.08%현저고우대조조10.64%,사주후연구조현효솔87.5%우우대조조68.8%,량조균무엄중불량반응.결론 문랍법신합병서필리능쾌속완해억욱증상,료효우우단용문랍법신,불량반응불증가,환자의종성호.
Objective To observe the curative effect and adverse reaction in the treatment of depres-sion by using venlafaxine combined with sulpiride. Methods The 64 hospital patients with depression were di-vided into two groups randomly. The study group of patients was treated with Venlafaxine Combined with Sulpiride while the controlled group of patients was treated with venlafaxine only. The curative effect and adverse reaction will be measured by Hamilton Depression Scale (HAMD) and Treatment Emergent Symptom Scale (TESS). Results The decrease rate in HAMD of the study group33.08% is higher than the controlled groupl0. 64% from the first week and the curative effect87.5% is better than the controlled group68.8% from the fourth week,there are no badly adverse reaction in two groups. Conclusion The treatment with venlafaxine combined with sulpiride can swiftly relieve the depression symptom and the curative effect is better than the treatment with venlafaxine only, and there is no increasing adverse reaction and the patients are willing to follow the course of treatment.