CAJ | 학술논문

目的探讨儿童下丘脑星形细胞瘤的临床特点,并对经胼胝体-穹窿间入路切除儿童下丘脑星形细胞瘤的治疗效果进行评估.方法采用经胼胝体-穹窿间人路对42例儿童下丘脑星形细胞瘤行手术切除,术后进行放疗.并对以上病例进行随访及回顾性分析.结果患者临床表现主要为颅内压增高和下丘脑损害.42例患者均伴有脑积水,手术入路采用经胼胝体-穹窿间入路,近全切除17例和大部分切除25例,无死亡病例.全部患者均行术后放疗.随访29例,其中25例能正常生活和学习,4例生活能自理.结论儿童原发于下丘脑的星形细胞瘤同原发于其他部位的视交叉下丘脑星形细胞瘤相比其临床表现及神经放射学检查有自身的特点,这些特点决定了经胼胝体-穹窿间入路是切除此类肿瘤主要有效的治疗方法,手术不要求全切肿瘤,术后辅以放射治疗,疗效满意.
목적 탐토인동하구뇌성형세포류적림상특점,병대경변지체-궁륭간입로절제인동하구뇌성형세포류적치료효과진행평고.방법 채용경변지체-궁륭간인로대42례인동하구뇌성형세포류행수술절제,술후진행방료.병대이상병례진행수방급회고성분석.결과 환자림상표현주요위로내압증고화하구뇌손해.42례환자균반유뇌적수,수술입로채용경변지체-궁륭간입로,근전절제17례화대부분절제25례,무사망병례.전부환자균행술후방료.수방29례,기중25례능정상생활화학습,4례생활능자리.결론 인동원발우하구뇌적성형세포류동원발우기타부위적시교차하구뇌성형세포류상비기림상표현급신경방사학검사유자신적특점,저사특점결정료경변지체-궁륭간입로시절제차류종류주요유효적치료방법,수술불요구전절종류,술후보이방사치료,료효만의.
Objective To explore the clinical features, diagnosis and efficiency of transcallosal-interforniceal approach treatment of hypothalamic astrocytoma in children. Methods A total of 42 pediatric cases of hypothalamic astrocytoma were operated by transcallosal-interforniceal approach. All cases received post-operative radiotherapy and follow-up visits. The clinical and imaging data were analyzed retrospectively.Results High ICP and hypothalamic lesions were the main clinical manifestations. All patients suffering from hydrocephalus were operated by transcallosal-interforniceal approach. Seventeen cases received subtotal resection and 25 in great part. None died from operation. All cases received post-operative radiotherapy.Twenty-nine cases were followed up for 1 to 7 years. Among which, 25 led a normal life and 4 stayed in a fair condition. Conclusions Hypothalamic astrocytom in children have some characteristic in clinical manifestations and neuroradiological examinations. Transcallosal-interforniceal approach is an effective method of treating hypothalamic astrocytom in children. Total removal is not imperative. And radiotherapy should be performed.