检验医学
檢驗醫學
검험의학
LABORATORY MEDICINE
2009年
12期
889-890
,共2页
梅毒%细胞免疫%淋巴细胞亚群
梅毒%細胞免疫%淋巴細胞亞群
매독%세포면역%림파세포아군
Syphilis%Cellular immunity%Lymphocyte subsets
目的 探讨二期梅毒患者外周血细胞免疫水平.方法 应用流式细胞仪检测40例二期梅毒患者的外周血T淋巴细胞亚群及自然杀伤(NK)细胞,并以42名健康人的检测结果 作对照,比较2组之间的差异.结果 二期梅毒患者外周血CD3细胞与对照组比较差异无统计学意义(P>0.05),CD4、CD4/CD8及NK细胞数显著低于对照组 (P<0.05),CD8细胞数高于对照组(P<0.05).结论 二期梅毒患者存在细胞免疫功能异常,这可能是造成患者体内病原体不能完全清除的原因之一.
目的 探討二期梅毒患者外週血細胞免疫水平.方法 應用流式細胞儀檢測40例二期梅毒患者的外週血T淋巴細胞亞群及自然殺傷(NK)細胞,併以42名健康人的檢測結果 作對照,比較2組之間的差異.結果 二期梅毒患者外週血CD3細胞與對照組比較差異無統計學意義(P>0.05),CD4、CD4/CD8及NK細胞數顯著低于對照組 (P<0.05),CD8細胞數高于對照組(P<0.05).結論 二期梅毒患者存在細胞免疫功能異常,這可能是造成患者體內病原體不能完全清除的原因之一.
목적 탐토이기매독환자외주혈세포면역수평.방법 응용류식세포의검측40례이기매독환자적외주혈T림파세포아군급자연살상(NK)세포,병이42명건강인적검측결과 작대조,비교2조지간적차이.결과 이기매독환자외주혈CD3세포여대조조비교차이무통계학의의(P>0.05),CD4、CD4/CD8급NK세포수현저저우대조조 (P<0.05),CD8세포수고우대조조(P<0.05).결론 이기매독환자존재세포면역공능이상,저가능시조성환자체내병원체불능완전청제적원인지일.
Objective To investigate the levels of cellular immunity of peripheral blood in patients with secondary syphilis. Methods The levels of T lymphocytes and natural killer (NK) cells of peripheral blood in 40 patients with secondary syphilis were determined by flow cytometry, and the results were compared with those in 42 healthy controls. Results There was no significant difference in the levels of CD3 cell of peripheral blood between the patients with secondary syphilis and the healthy controls (P>0.05), and the levels of CD4, CD4/CD8 and NK cells were significantly lower than those in the healthy controls (P<0.05). CD8 cell count was higher than that in the healthy controls (P<0.05). Conclusions Patients with secondary syphilis are with cellular immune dysfunction, which may be one of the reasons why pathogens in patients can not be completely removed.
