CAJ | 학술논문

本文对霞水母胶原蛋白活性肽和寡肽胶原的抗疲劳作用进行了研究.试验中分别以25、50、100 mg/kg剂量的霞水母胶原蛋白活性肽和寡肽胶原给小鼠连续灌胃30 d,然后进行小鼠负重游泳试验、血清尿素氮、肝糖原及血乳酸含量测定.结果显示,两种受试物各剂量组小鼠的游泳时间明显长于对照组(P<0.05或P<0.01),各剂量组小鼠运动后血清尿素氮含量及乳酸曲线下面积均低于对照组(P<0.01);各剂量组的小鼠游泳后肝糖原含量和空白对照组比较均有不同程度的提高.从而表明,霞水母胶原蛋白活性肽和寡肽胶原均具有抗疲劳作用.
본문대하수모효원단백활성태화과태효원적항피노작용진행료연구.시험중분별이25、50、100 mg/kg제량적하수모효원단백활성태화과태효원급소서련속관위30 d,연후진행소서부중유영시험、혈청뇨소담、간당원급혈유산함량측정.결과현시,량충수시물각제량조소서적유영시간명현장우대조조(P<0.05혹P<0.01),각제량조소서운동후혈청뇨소담함량급유산곡선하면적균저우대조조(P<0.01);각제량조적소서유영후간당원함량화공백대조조비교균유불동정도적제고.종이표명,하수모효원단백활성태화과태효원균구유항피노작용.
The effects of a novel collagen peptide and a novel oligopeptide from Cyanea nozakii on the anti-fatigue activi-ties of mice were investigated in this paper.Collagen peptide solution and oligopeptide solution were administered orally to the mice for30 days with the dosage of 25,50,and 100 mg/kg.The loading forced swimming time,serum urea nitro-gen,glycogen content in liver, and blood lactic value were tested.The results showed that all of the dosage levels of each test group could prolong the swimming time of mice (P <0.05 or P <0.01) ;Each dosage could reduce the quantity of blood urea nitrogen and decrease the content of the lactic acid in blood of mice evidently (P <0.01) ;And each dosage levels of the two tests could higher increase the glycogen content in liver inequality compared with the control group.It is suggested that the novel collagen peptide and oligopeptide from Cyanea nozak/i possessed the activity of promoting the anti-fatigue activity of mice.