中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2012年
6期
728-730
,共3页
杨中龙%陈芳%张春燕%陈志
楊中龍%陳芳%張春燕%陳誌
양중룡%진방%장춘연%진지
消旋山莨菪碱%减缓近视%矫正眼镜
消鏇山莨菪堿%減緩近視%矯正眼鏡
소선산랑탕감%감완근시%교정안경
Racemic anisodamine%Slow down myopia%Corrective glasses
目的 探讨使用消旋山莨菪碱滴眼液联合配戴矫正眼镜对学生近视进展的影响.方法 选取2007年7月1～30日来眼科医院近视防控科就诊的89例低度青少年近视患者.随机分为治疗组51例和对照组38例.治疗组使用0.5％消旋山莨菪碱滴眼液早晚各1次,每次1～2滴,连续使用1年,同时联合配戴矫正眼镜；对照组常规配戴矫正眼镜,局部和全身不使用任何药物.所有患者在受试前均接受眼部全面健康检查,散瞳后进行医学验光等效球镜(-1.98±1.22)DS,1年后两组进行视力、屈光度、眼轴、眼压及角膜曲率检查,并进行统计学分析.结果 1年后全程使用0.5％消旋山莨菪碱滴眼液43例(86眼)视力下降率为41.86％,对照组36例(72眼)为86.11％,两组比较差异有统计学意义P =0.0l.近视进展:治疗组(-0.43±0.45)D；对照组(-0.96±0.42)D,两组比较有统计学意义P＜0.01.眼轴增长:治疗组(0.11±0.21) mm,对照组(0.66±0.24)mm,对比有统计学意义P＜0.01.眼压和角膜曲率两组1年前后比较无差异P ＞0.05.结论 使用0.5％的消旋山莨菪碱滴眼液联合配戴矫正眼镜,使用安全、方便.有效减缓部分学生近视的进展.
目的 探討使用消鏇山莨菪堿滴眼液聯閤配戴矯正眼鏡對學生近視進展的影響.方法 選取2007年7月1～30日來眼科醫院近視防控科就診的89例低度青少年近視患者.隨機分為治療組51例和對照組38例.治療組使用0.5％消鏇山莨菪堿滴眼液早晚各1次,每次1～2滴,連續使用1年,同時聯閤配戴矯正眼鏡；對照組常規配戴矯正眼鏡,跼部和全身不使用任何藥物.所有患者在受試前均接受眼部全麵健康檢查,散瞳後進行醫學驗光等效毬鏡(-1.98±1.22)DS,1年後兩組進行視力、屈光度、眼軸、眼壓及角膜麯率檢查,併進行統計學分析.結果 1年後全程使用0.5％消鏇山莨菪堿滴眼液43例(86眼)視力下降率為41.86％,對照組36例(72眼)為86.11％,兩組比較差異有統計學意義P =0.0l.近視進展:治療組(-0.43±0.45)D；對照組(-0.96±0.42)D,兩組比較有統計學意義P＜0.01.眼軸增長:治療組(0.11±0.21) mm,對照組(0.66±0.24)mm,對比有統計學意義P＜0.01.眼壓和角膜麯率兩組1年前後比較無差異P ＞0.05.結論 使用0.5％的消鏇山莨菪堿滴眼液聯閤配戴矯正眼鏡,使用安全、方便.有效減緩部分學生近視的進展.
목적 탐토사용소선산랑탕감적안액연합배대교정안경대학생근시진전적영향.방법 선취2007년7월1～30일래안과의원근시방공과취진적89례저도청소년근시환자.수궤분위치료조51례화대조조38례.치료조사용0.5％소선산랑탕감적안액조만각1차,매차1～2적,련속사용1년,동시연합배대교정안경；대조조상규배대교정안경,국부화전신불사용임하약물.소유환자재수시전균접수안부전면건강검사,산동후진행의학험광등효구경(-1.98±1.22)DS,1년후량조진행시력、굴광도、안축、안압급각막곡솔검사,병진행통계학분석.결과 1년후전정사용0.5％소선산랑탕감적안액43례(86안)시력하강솔위41.86％,대조조36례(72안)위86.11％,량조비교차이유통계학의의P =0.0l.근시진전:치료조(-0.43±0.45)D；대조조(-0.96±0.42)D,량조비교유통계학의의P＜0.01.안축증장:치료조(0.11±0.21) mm,대조조(0.66±0.24)mm,대비유통계학의의P＜0.01.안압화각막곡솔량조1년전후비교무차이P ＞0.05.결론 사용0.5％적소선산랑탕감적안액연합배대교정안경,사용안전、방편.유효감완부분학생근시적진전.
Objective To investigate the use of racemic anisodamine eye drops combined with corrective glasses for student myopia progression effects. Methods Eighty-nine patients with low-grade myopia were selected from myopia prevention and control department of eye hospital from July 1,2007 to July 30,2007,and were randomly divided into treatment group of 51 cases and control group of 38 cases.The treatment group used 0.5％ racemic anisodamine eye drops 1time both in the morning and in the evening with each time contained 1-2 drops,continuous use for 1 year,at the same time wore corrective glasses; the control group received routine to wear corrective glasses,and neither local nor systemic drugs were used.All patients had ocular comprehensive health examination,medical optometry before the test,spherical equivalent after mydriasis (-1.98±1.22) DS.After 1 year,the two groups received examination of visual acuity,refraction,intraocular pressure,ocular axis,corneal curvature,and statistics analysis was performed.Results One year after full use of 0.5％ racemic anisodamine eye drops in 43 cases (86 eyes),vision decrease rate was 41.86％,36 cases (72 eyes) was 86.11％ in control group,there was statictically significant difference between two groups of P=0.01.Myopia progression:treatment group was (- 0.43±0.45) D; control group (-0.96±0.42) D,two groups had statistically significant at P ＜ 0.01.Axial growth:the treatment group (0.11±0.21) mm,the control group (0.66±0.24) mm,contrast was statistically significant at P ＜ 0.01.Intraocular pressure and corneal curvature in two groups before and after 1 year had no significant difference compared in two groups P ＞ 0.05.Conclusions Using 0.5％ racemic anisodamine eye drops combined with corrective glasses is safe,convenient and effective slowing down myopia progression in some students.
